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- 抗原 See all MAML1 抗体
- MAML1 (Mastermind-Like 1 (MAML1))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MAML1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein corresponding to Mouse MAML1
- Top Product
- Discover our top product MAML1 Primary Antibody
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anti-Mastermind-Like 1 (MAML1) (N-Term) antibody
MAML1 适用: 人, 小鼠 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mastermind-Like 1 (MAML1) (AA 1-45) antibodyMAML1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mastermind-Like 1 (MAML1) (N-Term) antibodyVerified MAML1 适用: 人 ELISA, WB, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Mastermind-Like 1 (MAML1) (AA 655-754) antibodyMAML1 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Mastermind-Like 1 (MAML1) (AA 1-300) antibodyMAML1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Mastermind-Like 1 (MAML1) (AA 198-225) antibodyMAML1 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB18757 unconjugated
anti-Mastermind-Like 1 (MAML1) (AA 205-234), (Middle Region) antibodyMAML1 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB (H,M) 1: 500-1: 1000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- PBS, pH 7.4, 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
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- 抗原
- MAML1 (Mastermind-Like 1 (MAML1))
- 别名
- MAML1 (MAML1 产品)
- 别名
- mam1 antibody, mam-1 antibody, xmam1 antibody, MAML1 antibody, AI644666 antibody, AW743257 antibody, D930008C07Rik antibody, Mam-1 antibody, Mam1 antibody, mKIAA0200 antibody, mastermind like transcriptional coactivator 1 L homeolog antibody, mastermind like transcriptional coactivator 1 antibody, mastermind like 1 (Drosophila) antibody, mastermind-like transcriptional coactivator 1 antibody, maml1.L antibody, MAML1 antibody, Maml1 antibody
- 背景
- MAML1, also named as KIAA0200 and Mam-1 , belongs to the mastermind family. It acts as a transcriptional coactivator for NOTCH proteins. MAML1 has been shown to amplify NOTCH-induced transcription of HES1. It enhances phosphorylation and proteolytic turnover of the NOTCH intracellular domain in the nucleus through interaction with CDK8. MAML1 binds to CREBBP/CBP which promotes nucleosome acetylation at NOTCH enhancers and activates transcription. Induces phosphorylation and localization of CREBBP to nuclear foci. It plays a role in hematopoietic development by regulating NOTCH-mediated lymphoid cell fate decisions. The calculated molecular weight of MAML1 is 108 kDa, but modified MAML1 is about 120-130 kDa.
- 分子量
- 130 kDa
- 基因ID
- 103806
- NCBI登录号
- NP_780543
- UniProt
- Q6T264
- 途径
- Notch Signaling, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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