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ACVR2B 抗体

ACVR2B 适用: 人 IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7263899
发货至: 中国
  • 抗原 See all ACVR2B 抗体
    ACVR2B (Activin A Receptor, Type IIB (ACVR2B))
    适用
    • 72
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    宿主
    • 70
    • 7
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    克隆类型
    • 75
    • 5
    多克隆
    标记
    • 37
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    This ACVR2B antibody is un-conjugated
    应用范围
    • 76
    • 28
    • 23
    • 13
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    • 8
    • 3
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    • 1
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    Immunofluorescence (IF)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    A synthetic peptide of human ACVR2B (NP_001097.2).
    亚型
    IgG
    Top Product
    Discover our top product ACVR2B Primary Antibody
  • 应用备注
    IF 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    ACVR2B (Activin A Receptor, Type IIB (ACVR2B))
    别名
    ACVR2B (ACVR2B 产品)
    别名
    ACVR2B antibody, XAR1 antibody, actr-iib antibody, actriib antibody, ACTRIIB antibody, ActR-IIB antibody, HTX4 antibody, ActRIIB antibody, actr2b antibody, actrIIb antibody, wu:fj97d11 antibody, activin A receptor type 2B antibody, activin A receptor type 2B L homeolog antibody, activin A receptor type 2Ba antibody, activin receptor IIB antibody, ACVR2B antibody, acvr2b antibody, acvr2b.L antibody, Acvr2b antibody, acvr2ba antibody
    背景
    Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor.
    基因ID
    93
    UniProt
    Q13705
    途径
    Hormone Transport, Cancer Immune Checkpoints
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