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- 抗原 See all PRKAA1/PRKAA2 products
- PRKAA1/PRKAA2 (AMPK1/AMPK2)
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PRKAA1/PRKAA2 antibody is un-conjugated
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应用范围
- Immunofluorescence (IF)
- 产品特性
- Polyclonal Antibody
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein of human PRKAA1/PRKAA2
- 亚型
- IgG
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anti-AMPK1/AMPK2 (pThr172), (pThr183) antibody
适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-AMPK1/AMPK2 (pThr172), (pThr183) antibody适用: 人, 小鼠, 大鼠, Pig, 绵羊 WB, ELISA, IF (cc), IHC (p), FACS, IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-AMPK1/AMPK2 (pThr172), (pThr183) antibody (Cy7)适用: 人, 小鼠, 大鼠, Pig, 绵羊 WB, IF (cc), FACS, IF (p) 宿主: 兔 Polyclonal Cy7
anti-AMPK1/AMPK2 (AA 14-47), (N-Term) antibody适用: 小鼠 WB 宿主: 兔 Polyclonal RB43852 unconjugated
anti-AMPK1/AMPK2 (Ser1071) antibody适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-AMPK1/AMPK2 (Center) antibody适用: 人, 小鼠, 大鼠, Pig, 小鸡 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-AMPK1/AMPK2 (pSer172), (pSer183) antibody适用: 人, 小鼠, 大鼠, Pig, 小鸡 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- IF 1:50-1:100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- PRKAA1/PRKAA2 (AMPK1/AMPK2)
- 别名
- AMPKa1/AMPKa2 (PRKAA1/PRKAA2 产品)
- 别名
- AMPK antibody, AMPK2 antibody, AMPKa2 antibody, PRKAA antibody, Ampk antibody, Ampka2 antibody, 2310008I11Rik antibody, A830082D05 antibody, AMPKalpha2 antibody, protein kinase AMP-activated catalytic subunit alpha 2 antibody, protein kinase, AMP-activated, alpha 2 catalytic subunit antibody, PRKAA2 antibody, Prkaa2 antibody
- 背景
- The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed./The protein encoded by this gene is a catalytic subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. Studies of the mouse counterpart suggest that this catalytic subunit may control whole-body insulin sensitivity and is necessary for maintaining myocardial energy homeostasis during ischemia.
- 基因ID
- 5562, 5563
- UniProt
- Q13131, P54646
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