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CTCF 抗体

CTCF 适用: 人, 小鼠, 大鼠, 猴 IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7255588
发货至: 中国
  • 抗原 See all CTCF 抗体
    CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))
    适用
    • 58
    • 36
    • 31
    • 8
    • 8
    • 7
    • 7
    • 5
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    • 4
    • 4
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠, 猴
    宿主
    • 48
    • 8
    • 2
    • 1
    • 1
    克隆类型
    • 38
    • 22
    多克隆
    标记
    • 46
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This CTCF antibody is un-conjugated
    应用范围
    • 41
    • 11
    • 10
    • 9
    • 9
    • 9
    • 8
    • 8
    • 3
    • 2
    • 1
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    • 1
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    Immunohistochemistry (IHC), Immunofluorescence (IF)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human CTCF (NP_006556.1).
    亚型
    IgG
    Top Product
    Discover our top product CTCF Primary Antibody
  • 应用备注
    IHC 1:50-1:200 IF 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    CTCF (CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))
    别名
    CTCF (CTCF 产品)
    别名
    im:7152666 antibody, CTCF antibody, xctcf antibody, AW108038 antibody, CCCTC-binding factor antibody, CCCTC-binding factor (zinc finger protein) antibody, CTCF antibody, ctcf antibody, Ctcf antibody
    背景
    This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    基因ID
    10664
    UniProt
    P49711
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