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CTCF 抗体

(CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))
This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010].
CTCF 抗体  (AA 1-260) CTCF 抗体  (AA 1-260) CTCF 抗体 (AA 1-260) (ABIN3021507)

CTCF 适用: 人 WB, IHC, IF, ChIP, IP 宿主: 兔 Polyclonal unconjugated

CTCF 抗体 CTCF 抗体 CTCF 抗体 (ABIN7255588)

CTCF 适用: 人, 小鼠, 大鼠, 猴 IHC, IF 宿主: 兔 Polyclonal unconjugated

CTCF 抗体 CTCF 抗体 CTCF 抗体 (ABIN7266164)

CTCF 适用: 人 WB, IF, ChIP, IP 宿主: 兔 Monoclonal unconjugated

CTCF 抗体 by Grade

Find CTCF 抗体 with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

CTCF 抗体 by 适用

Find CTCF 抗体 for a variety of species such as anti-Human CTCF, anti-Mouse CTCF, anti-Rat CTCF. The species listed below are among those available. Click on a link to go to the corresponding products.

CTCF 抗体 by 应用范围

Find CTCF 抗体 validated for a specific application such as WB, IHC, IF, IHC (p). Some of the available applications are listed below. Click on a link to go to the corresponding products.

CTCF 抗体 by 抗体来源

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CTCF 抗体 by 抗原表位

Find CTCF 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

CTCF 抗体 by 克隆形成能力

Find available monoclonal or polyclonal CTCF 抗体. Click on a link to go to the corresponding products.

CTCF 抗体 by 克隆

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CTCF 抗体 by 标记

Find CTCF 抗体 with a specific conjugate such as Alexa Fluor 488, Alexa Fluor 555, Alexa Fluor 594. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular CTCF 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IF, ChIP, IP
Validations
  • (6)
Cat. No. ABIN3021507
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey, Mouse, Rat
Application IHC, IF
Validations
  • (5)
Cat. No. ABIN7255588
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, ChIP, IP
Validations
  • (5)
Cat. No. ABIN7266164
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (4)
Cat. No. ABIN6261079
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, IF, ChIP, ICC, ChIP-seq
Validations
  • (1)
  • (4)
Cat. No. ABIN2668282
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, ChIP
Validations
  • (3)
Cat. No. ABIN7172779
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (3)
Cat. No. ABIN6243085
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF, ChIP, ICC, ChIP-seq, CUT&Tag, SSA
Validations
  • (3)
Cat. No. ABIN6971556
Quantity 100 μL
Datasheet Datasheet

Application WB, IHC, IHC (p)
Validations
  • (3)
Cat. No. ABIN6736709
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA
Validations
  • (1)
  • (2)
Cat. No. ABIN964615
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (4)
Cat. No. ABIN3043817
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
  • (2)
Cat. No. ABIN703976
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN564648
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN5649894
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p)
Validations
  • (2)
Cat. No. ABIN5649893
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our CTCF 抗体

Moriguchi, Yu, Takai, Hayashi, Satoh, Suzuki, Ohneda, Yamamoto: "The Human GATA1 Gene Retains a 5' Insulator That Maintains Chromosomal Architecture and GATA1 Expression Levels in Splenic Erythroblasts." in: Molecular and cellular biology, Vol. 35, Issue 10, pp. 1825-37, (2015) (PubMed).

Majumder, Rupp, Yang-Iott, Koues, Kyle, Bassing, Oltz: "Domain-Specific and Stage-Intrinsic Changes in Tcrb Conformation during Thymocyte Development." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 3, pp. 1262-72, (2015) (PubMed).

Martínez, Cruz, Lu, Plasschaert, Deng, Rivera-Molina, Bartolomei, Lieberman, Tang: "CTCF binding to the first intron of the major immediate early (MIE) gene of human cytomegalovirus (HCMV) negatively regulates MIE gene expression and HCMV replication." in: Journal of virology, Vol. 88, Issue 13, pp. 7389-401, (2014) (PubMed).

Lai, Fatemi, Dhasarathy, Malone, Sobol, Geigerman, Jaye, Mav, Shah, Li, Wade: "DNA methylation prevents CTCF-mediated silencing of the oncogene BCL6 in B cell lymphomas." in: The Journal of experimental medicine, Vol. 207, Issue 9, pp. 1939-50, (2010) (PubMed).

Grbesa, Marinkovic, Ivkic, Kruslin, Novak-Kujundzic, Pegan, Bogdanovic, Bedekovic, Gall-Troselj: "Loss of imprinting of IGF2 and H19, loss of heterozygosity of IGF2R and CTCF, and Helicobacter pylori infection in laryngeal squamous cell carcinoma." in: Journal of molecular medicine (Berlin, Germany), Vol. 86, Issue 9, pp. 1057-66, (2008) (PubMed).

Majumder, Gomez, Chadwick, Boss: "The insulator factor CTCF controls MHC class II gene expression and is required for the formation of long-distance chromatin interactions." in: The Journal of experimental medicine, Vol. 205, Issue 4, pp. 785-98, (2008) (PubMed).

Stedman, Kang, Lin, Kissil, Bartolomei, Lieberman: "Cohesins localize with CTCF at the KSHV latency control region and at cellular c-myc and H19/Igf2 insulators." in: The EMBO journal, Vol. 27, Issue 4, pp. 654-66, (2008) (PubMed).

Bell, West, Felsenfeld: "The protein CTCF is required for the enhancer blocking activity of vertebrate insulators." in: Cell, Vol. 98, Issue 3, pp. 387-96, (1999) (PubMed).

Filippova, Lindblom, Meincke, Klenova, Neiman, Collins, Doggett, Lobanenkov: "A widely expressed transcription factor with multiple DNA sequence specificity, CTCF, is localized at chromosome segment 16q22.1 within one of the smallest regions of overlap for common deletions in breast and prostate cancers." in: Genes, chromosomes & cancer, Vol. 22, Issue 1, pp. 26-36, (1998) (PubMed).

Filippova, Fagerlie, Klenova, Myers, Dehner, Goodwin, Neiman, Collins, Lobanenkov: "An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes." in: Molecular and cellular biology, Vol. 16, Issue 6, pp. 2802-13, (1996) (PubMed).

Aliases for CTCF 抗体

CCCTC-binding factor (CTCF) 抗体
CCCTC-binding factor (zinc finger protein) (ctcf) 抗体
CCCTC-binding factor (ctcf) 抗体
CCCTC-binding factor (Ctcf) 抗体
AW108038 抗体
CTCF 抗体
im:7152666 抗体
xctcf 抗体
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