CTCF 抗体
(CCCTC-Binding Factor (Zinc Finger Protein) (CTCF))
This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010].
| Catalog no. | 产品 | 适用 | 宿主 / 克隆类型 | 应用 | 价格和交货时间 |
|---|---|---|---|---|---|
| Recombinant CTCF 抗体 (AA 650-700) | 人, 小鼠 | 兔 Monoclonal |
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| CTCF 抗体 (AA 1-260) | 人 | 兔 Polyclonal |
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| CTCF 抗体 | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| Recombinant CTCF 抗体 (Sortase,His tag,AVI tag) | 人 | 兔 Monoclonal |
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| Recombinant CTCF 抗体 | 人 | 兔 Monoclonal |
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| CTCF 抗体 (AA 334-364) | 人 | 兔 Polyclonal |
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| CTCF 抗体 (N-Term) | 人, 小鼠, 大鼠, Cow, 犬, 兔, 猴, 马, 豚鼠, Bat, 小鸡, Hamster | 兔 Polyclonal |
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| CTCF 抗体 (C-Term) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| CTCF 抗体 (AA 1-260) | 人 | 兔 Polyclonal |
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| CTCF 抗体 (AA 451-550) | 人 | 兔 Polyclonal |
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| CTCF 抗体 | 人, 猴 | 小鼠 Monoclonal |
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| CTCF 抗体 | 人 | 小鼠 Monoclonal |
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| CTCF 抗体 (AA 1-100) | 人 | 小鼠 Polyclonal |
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| CTCF 抗体 (AA 521-727) | 人, 小鼠, 大鼠 | 兔 Polyclonal |
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| CTCF 抗体 (AA 185-216) | 人, 小鼠 | 兔 Polyclonal |
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| CTCF 抗体 (AA 445-727) | 人, 大鼠 | 小鼠 Monoclonal |
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| CTCF 抗体 (AA 650-700) | 人 | 兔 Polyclonal |
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| CTCF 抗体 (AA 181-230) | 人, 小鼠, 大鼠, Cow, 犬, 兔, 猴, Pig, 马, Bat | 兔 Polyclonal |
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| CTCF 抗体 (AA 650-700) | 人, 小鼠 | 兔 Polyclonal |
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| CTCF 抗体 (C-Term) | 人, 小鼠 | 小鼠 Monoclonal |
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Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- ICC (Immunocytochemistry: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- IP (Immunoprecipitation: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- BLR041F
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG
- 抗原表位
- AA 650-700
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF (Immunofluorescence: 有验证图片)
- ChIP (Chromatin Immunoprecipitation: 有验证图片)
- IP (Immunoprecipitation: 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-260
Primary Antibody
- IF (Immunofluorescence: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
Primary Antibody
- CUT&RUN (Cleavage Under Targets and Release Using Nuclease (CUT&RUN): 已在此应用中经过独立验证)
- WB (Western Blotting: 有验证图片)
- ChIP-seq (ChIP DNA-Sequencing: 有验证图片)
- ChIP (Chromatin Immunoprecipitation: 所列应用)
- CUT&Tag (Cleavage Under Targets and Tagmentation: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 标记
- Sortase,His tag,AVI tag
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG
Independently Validated
Primary Antibody
- WB (Western Blotting: 有验证图片)
- FACS (Flow Cytometry: 有验证图片)
- ICC (Immunocytochemistry: 有验证图片)
- 质量等级
- KD Validated
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Monoclonal
- 克隆
- 23GB3520
- 标记
- unconjugated
- 蛋白类型
- Recombinant Antibody
- 抗体亚型
- IgG
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB53773
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 334-364
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- WB (Western Blotting: 所列应用)
- 适用
- 人, 小鼠, 大鼠, Cow, 犬, 兔, 猴, 马, 豚鼠, Bat, 小鸡, Hamster
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- N-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IF/ICC (Immunofluorescence (fixed cells): 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- IHC (Immunohistochemistry: 所列应用)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- C-Term
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- ELISA (ELISA: 所列应用)
- ChIP (Chromatin Immunoprecipitation: 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 1-260
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 所列应用)
- IF (cc) (Immunofluorescence (Cultured Cells): 所列应用)
- IF (p) (Immunofluorescence (Paraffin-embedded Sections): 所列应用)
- IHC (fro) (Immunohistochemistry (Frozen Sections): 所列应用)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 451-550
Primary Antibody
- WB (Western Blotting: 有验证图片)
- ELISA (ELISA: 所列应用)
3 references - 适用
- 人, 猴
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 1D11
- 标记
- unconjugated
- 抗体亚型
- IgG1
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人
- 宿主
- 小鼠
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗原表位
- AA 1-100
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IHC (Immunohistochemistry: 有验证图片)
- IF (Immunofluorescence: 所列应用)
- ICC (Immunocytochemistry: 所列应用)
- FACS (Flow Cytometry: 所列应用)
- 适用
- 人, 小鼠, 大鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 521-727
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 克隆
- RB53771
- 标记
- unconjugated
- 抗体亚型
- Ig Fraction
- 抗原表位
- AA 185-216
Primary Antibody
- WB (Western Blotting: 有验证图片)
- 适用
- 人, 大鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- 1723CT382-14-9
- 标记
- unconjugated
- 抗体亚型
- IgG1 kappa
- 抗原表位
- AA 445-727
Primary Antibody
- IHC (Immunohistochemistry: 有验证图片)
- 适用
- 人
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 650-700
Primary Antibody
- WB (Western Blotting: 有验证图片)
- IP (Immunoprecipitation: 所列应用)
- IHC (fp) (Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections): 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 兔
- 克隆形成能力
- Polyclonal
- 标记
- unconjugated
- 抗体亚型
- IgG
- 抗原表位
- AA 650-700
Primary Antibody
- IHC (p) (Immunohistochemistry (Paraffin-embedded Sections): 有验证图片)
- WB (Western Blotting: 所列应用)
- IHC (Immunohistochemistry: 所列应用)
- 适用
- 人, 小鼠
- 宿主
- 小鼠
- 克隆形成能力
- Monoclonal
- 克隆
- AFfirm8049(AFP21846)
- 标记
- unconjugated
- 抗体亚型
- IgG1
- 抗原表位
- C-Term
Latest Publications for our CTCF 抗体
: "The Human GATA1 Gene Retains a 5' Insulator That Maintains Chromosomal Architecture and GATA1 Expression Levels in Splenic Erythroblasts." in: Molecular and cellular biology, Vol. 35, Issue 10, pp. 1825-37, (2015) (PubMed).
: "Domain-Specific and Stage-Intrinsic Changes in Tcrb Conformation during Thymocyte Development." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 3, pp. 1262-72, (2015) (PubMed).
: "CTCF binding to the first intron of the major immediate early (MIE) gene of human cytomegalovirus (HCMV) negatively regulates MIE gene expression and HCMV replication." in: Journal of virology, Vol. 88, Issue 13, pp. 7389-401, (2014) (PubMed).
: "DNA methylation prevents CTCF-mediated silencing of the oncogene BCL6 in B cell lymphomas." in: The Journal of experimental medicine, Vol. 207, Issue 9, pp. 1939-50, (2010) (PubMed).
: "Loss of imprinting of IGF2 and H19, loss of heterozygosity of IGF2R and CTCF, and Helicobacter pylori infection in laryngeal squamous cell carcinoma." in: Journal of molecular medicine (Berlin, Germany), Vol. 86, Issue 9, pp. 1057-66, (2008) (PubMed).
: "The insulator factor CTCF controls MHC class II gene expression and is required for the formation of long-distance chromatin interactions." in: The Journal of experimental medicine, Vol. 205, Issue 4, pp. 785-98, (2008) (PubMed).
: "Cohesins localize with CTCF at the KSHV latency control region and at cellular c-myc and H19/Igf2 insulators." in: The EMBO journal, Vol. 27, Issue 4, pp. 654-66, (2008) (PubMed).
: "The protein CTCF is required for the enhancer blocking activity of vertebrate insulators." in: Cell, Vol. 98, Issue 3, pp. 387-96, (1999) (PubMed).
: "A widely expressed transcription factor with multiple DNA sequence specificity, CTCF, is localized at chromosome segment 16q22.1 within one of the smallest regions of overlap for common deletions in breast and prostate cancers." in: Genes, chromosomes & cancer, Vol. 22, Issue 1, pp. 26-36, (1998) (PubMed).
: "An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes." in: Molecular and cellular biology, Vol. 16, Issue 6, pp. 2802-13, (1996) (PubMed).
: "Domain-Specific and Stage-Intrinsic Changes in Tcrb Conformation during Thymocyte Development." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 3, pp. 1262-72, (2015) (PubMed).
: "CTCF binding to the first intron of the major immediate early (MIE) gene of human cytomegalovirus (HCMV) negatively regulates MIE gene expression and HCMV replication." in: Journal of virology, Vol. 88, Issue 13, pp. 7389-401, (2014) (PubMed).
: "DNA methylation prevents CTCF-mediated silencing of the oncogene BCL6 in B cell lymphomas." in: The Journal of experimental medicine, Vol. 207, Issue 9, pp. 1939-50, (2010) (PubMed).
: "Loss of imprinting of IGF2 and H19, loss of heterozygosity of IGF2R and CTCF, and Helicobacter pylori infection in laryngeal squamous cell carcinoma." in: Journal of molecular medicine (Berlin, Germany), Vol. 86, Issue 9, pp. 1057-66, (2008) (PubMed).
: "The insulator factor CTCF controls MHC class II gene expression and is required for the formation of long-distance chromatin interactions." in: The Journal of experimental medicine, Vol. 205, Issue 4, pp. 785-98, (2008) (PubMed).
: "Cohesins localize with CTCF at the KSHV latency control region and at cellular c-myc and H19/Igf2 insulators." in: The EMBO journal, Vol. 27, Issue 4, pp. 654-66, (2008) (PubMed).
: "The protein CTCF is required for the enhancer blocking activity of vertebrate insulators." in: Cell, Vol. 98, Issue 3, pp. 387-96, (1999) (PubMed).
: "A widely expressed transcription factor with multiple DNA sequence specificity, CTCF, is localized at chromosome segment 16q22.1 within one of the smallest regions of overlap for common deletions in breast and prostate cancers." in: Genes, chromosomes & cancer, Vol. 22, Issue 1, pp. 26-36, (1998) (PubMed).
: "An exceptionally conserved transcriptional repressor, CTCF, employs different combinations of zinc fingers to bind diverged promoter sequences of avian and mammalian c-myc oncogenes." in: Molecular and cellular biology, Vol. 16, Issue 6, pp. 2802-13, (1996) (PubMed).
Aliases for CTCF 抗体
CCCTC-binding factor (CTCF) 抗体CCCTC-binding factor (zinc finger protein) (ctcf) 抗体
CCCTC-binding factor (ctcf) 抗体
CCCTC-binding factor (Ctcf) 抗体
AW108038 抗体
CTCF 抗体
im:7152666 抗体
xctcf 抗体
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