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TRAIL 抗体

TNFSF10 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7249904
发货至: 中国
  • 抗原 See all TRAIL (TNFSF10) 抗体
    TRAIL (TNFSF10) (Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))
    适用
    • 102
    • 31
    • 30
    • 4
    • 2
    人, 小鼠, 大鼠
    宿主
    • 78
    • 41
    • 1
    克隆类型
    • 81
    • 39
    多克隆
    标记
    • 66
    • 15
    • 10
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRAIL antibody is un-conjugated
    应用范围
    • 89
    • 34
    • 23
    • 22
    • 13
    • 13
    • 10
    • 9
    • 9
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB)
    产品特性
    Polyclonal Antibody
    纯化方法
    Affinity purification
    免疫原
    KLH conjugated Synthetic peptide corresponding to Mouse Trail
    亚型
    IgG
    Top Product
    Discover our top product TNFSF10 Primary Antibody
  • 应用备注
    WB 1:500-1:2000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.94 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 1 % BSA and 50 % glycerol, pH 7.4
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    TRAIL (TNFSF10) (Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))
    别名
    TRAIL (TNFSF10 产品)
    别名
    APO2L antibody, Apo-2L antibody, CD253 antibody, TL2 antibody, TRAIL antibody, A330042I21Rik antibody, AI448571 antibody, APO-2L antibody, Ly81 antibody, Trail antibody, tl2 antibody, apo2l antibody, cd253 antibody, trail antibody, apo-2l antibody, trail1 antibody, xtrail1 antibody, tnfsf10l2 antibody, zgc:92320 antibody, TNLG6A antibody, TNF superfamily member 10 antibody, tumor necrosis factor (ligand) superfamily, member 10 antibody, tumor necrosis factor superfamily member 10 antibody, TNF superfamily member 10 S homeolog antibody, TNFSF10 antibody, Tnfsf10 antibody, tnfsf10.S antibody, tnfsf10 antibody
    背景
    The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. This protein binds to several members of TNF receptor superfamily including TNFRSF10A/TRAILR1, TNFRSF10B/TRAILR2, TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and possibly also to TNFRSF11B/OPG. The activity of this protein may be modulated by binding to the decoy receptors TNFRSF10C/TRAILR3, TNFRSF10D/TRAILR4, and TNFRSF11B/OPG that cannot induce apoptosis. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    分子量

    Observed_MW: 33 kDa

    Calculated_MW: 33 kDa

    UniProt
    P50591, P50592
    途径
    Apoptosis, Positive Regulation of Endopeptidase Activity
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