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TIM3 抗体 (Extracellular Domain) (Biotin)

TIM 3 适用: 人 ELISA 宿主: 小鼠 Monoclonal 10C10 Biotin
产品编号 ABIN6992273
发货至: 中国
  • 抗原 See all TIM3 (TIM 3) 抗体
    TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))
    抗原表位
    • 20
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Extracellular Domain
    适用
    • 68
    • 34
    • 4
    • 3
    • 2
    • 1
    宿主
    • 48
    • 24
    • 22
    • 2
    小鼠
    克隆类型
    • 51
    • 44
    • 1
    单克隆
    标记
    • 58
    • 7
    • 7
    • 7
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TIM3 antibody is conjugated to Biotin
    应用范围
    • 43
    • 40
    • 34
    • 23
    • 12
    • 8
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA
    纯化方法
    TIM-3 Antibody is supplied as protein A purified IgG1.
    免疫原
    TIM-3 antibody was raised against the extracellular domain of human TIM-3
    克隆位点
    10C10
    亚型
    IgG1 kappa
    Top Product
    Discover our top product TIM 3 Primary Antibody
  • 应用备注
    TIM-3 antibody can be used for ELISA starting at 0.1 μ,g/mL.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    TIM-3 Antibody is supplied in PBS containing 1 % BSA and 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    TIM-3 antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
  • 抗原
    TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))
    别名
    TIM3 (TIM 3 产品)
    别名
    HAVCR2 antibody, MGC140131 antibody, HAVcr-2 antibody, KIM-3 antibody, TIM3 antibody, TIMD-3 antibody, TIMD3 antibody, Tim-3 antibody, TIM-3 antibody, Tim3 antibody, Timd3 antibody, tim3 antibody, hepatitis A virus cellular receptor 2 antibody, HAVCR2 antibody, Havcr2 antibody
    物质类
    Virus
    背景
    The immune checkpoint protein TIM3 is a member of the immunoglobulin superfamily and TIM family of proteins that was initially identified as a specific marker of fully differentiated IFN-? producing CD4 T helper 1 (Th1) and CD8 cytotoxic cells. It is a Th1-specific cell surface protein that regulates macrophage activation and negatively regulates Th1-mediated auto- and alloimmune responses, and is also highly expressed on regulatory T cells, monocytes, macrophages, and dendritic cells (1). TIM3 and PD-1 are co-expressed on most CD4 and CD8 T cells infiltrating solid tumors or in hematologic malignancy in mice, blocking TIM3 in conjugation with a PD-1 blockade increases the functionality of exhausted T cells and synergizes with to inhibit tumor growth (2,3).
    基因ID
    84868
    NCBI登录号
    NP_116171
    UniProt
    Q8TDQ0
    途径
    Regulation of Lipid Metabolism by PPARalpha, Cancer Immune Checkpoints
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