Nephrin 抗体 (AA 1100-1150)
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- 抗原 See all Nephrin (NPHS1) 抗体
- Nephrin (NPHS1) (Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1))
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抗原表位
- AA 1100-1150
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Nephrin antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
- 纯化方法
- Nephrin antibody is affinity chromatography purified via peptide column.
- 免疫原
- Anti-Nephrin antibody was raised against a peptide corresponding to 15 amino acids near the center of human Nephrin. The immunogen is located within amino acids 1100-1150 of Nephrin.
- 亚型
- IgG
- Top Product
- Discover our top product NPHS1 Primary Antibody
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anti-Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1) (AA 23-92) antibody
NPHS1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1) (AA 451-550) antibodyNPHS1 适用: 人, 小鼠, 大鼠, 犬 FACS 宿主: 兔 Polyclonal unconjugated
anti-Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1) (AA 27-234) antibodyNPHS1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1) (AA 27-234) antibodyNPHS1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C8 unconjugated
anti-Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1) (AA 23-257) antibodyNPHS1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1) (AA 1191-1219), (Tyr1210) antibodyNPHS1 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB28264 unconjugated
anti-Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1) (C-Term) antibodyNPHS1 适用: 人, 小鼠, 大鼠 WB, IHC (p), IF, EIA 宿主: 兔 Polyclonal unconjugated
anti-Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1) (AA 39-144) antibodyNPHS1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1) (AA 39-106) antibodyNPHS1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1) (AA 33-122) antibodyNPHS1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D2 unconjugated
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- 应用备注
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WB: 1-2 μ,g/mL, IHC: 5 μ,g/mL, IF: 20 μ,g/mL.
Antibody validated: Western Blot in human and mouse samples, Immunohistochemistry in human samples, Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Nephrin antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- Nephrin antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- 抗原
- Nephrin (NPHS1) (Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1))
- 别名
- Nephrin (NPHS1 产品)
- 别名
- NPHS1 antibody, nphs1l antibody, nphs1 antibody, CNF antibody, NPHN antibody, nephrin antibody, NephrinB antibody, NPHS1, nephrin antibody, nephrosis 1, congenital, Finnish type (nephrin) antibody, NPHS1 nephrin S homeolog antibody, nephrin antibody, NPHS1 nephrin antibody, nephrosis 1, nephrin antibody, NPHS1 antibody, nphs1 antibody, nphs1.S antibody, LOC5579127 antibody, Nphs1 antibody
- 背景
- Nephrin is strongly expressed in renal glomeruli and is a member of the immunoglobulin family of cell adhesion molecules. Mutations in the Nephrin gene result in congenital nephrotic syndrome, an autosomal-recessive disorder characterized by massive proteinuria in utero and nephrosis at birth (1). Renal glomeruli allow normal kidneys to filter plasma so that it is very pure. Nephrin is expressed in the podocyte slit-diaphragm of the renal glomeruli in a manner that suggests that Nephrin molecules homodimerize in an anti-parallel fashion similar to cadherin interactions in adherens junctions. Thus, Nephrin may constitute the entire extracellular structure of the slit-diaphragm (2,3).
- 分子量
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Predicted: 125, 137 kDa
Observed: 125 kDa - 基因ID
- 4648
- NCBI登录号
- NP_004637
- UniProt
- O60500
- 途径
- Regulation of Actin Filament Polymerization, Skeletal Muscle Fiber Development
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