Nephrin 抗体 (Tyr1210)
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北京 101111
Quick Overview for Nephrin 抗体 (Tyr1210) (ABIN654375)
抗原
See all Nephrin (NPHS1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1191-1219, Tyr1210
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This Nephrin antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1191-1219 amino acids from human Nephrin.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. WB: 1:1000. WB: 1:2000. FC: 1:10~50
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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有效期
- 6 months
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- Nephrin (NPHS1) (Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1))
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别名
- Nephrin
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背景
- This gene encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney. The gene is primarily expressed in renal tissues, and the protein is a type-1 transmembrane protein found at the slit diaphragm of glomerular podocytes. The slit diaphragm is thought to function as an ultrafilter to exclude albumin and other plasma macromolecules in the formation of urine. Mutations in this gene result in Finnish-type congenital nephrosis 1, characterized by severe proteinuria and loss of the slit diaphragm and foot processes.
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分子量
- 134742
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基因ID
- 4868
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NCBI登录号
- NP_004637
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UniProt
- O60500
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途径
- Regulation of Actin Filament Polymerization, Skeletal Muscle Fiber Development
抗原
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