Nephrin 抗体 (C-Term)
(2 references)-
- 抗原 See all Nephrin (NPHS1) 抗体
- Nephrin (NPHS1) (Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Nephrin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects Nephrin.
- 纯化方法
- Peptide affinity chromatography
- 免疫原
- Nephrin antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human Nephrin.
- 亚型
- IgG
- Top Product
- Discover our top product NPHS1 Primary Antibody
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anti-Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1) (AA 23-92) antibody
NPHS1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1) (AA 451-550) antibodyNPHS1 适用: 人, 小鼠, 大鼠, 犬 FACS 宿主: 兔 Polyclonal unconjugated
anti-Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1) (AA 27-234) antibodyNPHS1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1) (AA 27-234) antibodyNPHS1 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C8 unconjugated
anti-Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1) (AA 23-257) antibodyNPHS1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1) (AA 1191-1219), (Tyr1210) antibodyNPHS1 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB28264 unconjugated
anti-Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1) (AA 39-144) antibodyNPHS1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1) (AA 39-106) antibodyNPHS1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1) (AA 33-122) antibodyNPHS1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3D2 unconjugated
anti-Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1) (AA 465-528) antibodyNPHS1 适用: 人, 小鼠, 大鼠 WB, ELISA, IP, IHC (p) 宿主: 兔 Monoclonal Y17-R unconjugated
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- 应用备注
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ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- PBS containing 0.02 % Sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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: "Targeting reduction of proteinuria in glomerulonephritis: Maximizing the antifibrotic effect of valsartan by protecting podocytes." in: Journal of the renin-angiotensin-aldosterone system : JRAAS, Vol. 15, Issue 2, pp. 177-89, (2015) (PubMed).
: "A plasminogen activator inhibitor type 1 mutant retards diabetic nephropathy in db/db mice by protecting podocytes." in: Experimental physiology, Vol. 99, Issue 5, pp. 802-15, (2014) (PubMed).
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: "Targeting reduction of proteinuria in glomerulonephritis: Maximizing the antifibrotic effect of valsartan by protecting podocytes." in: Journal of the renin-angiotensin-aldosterone system : JRAAS, Vol. 15, Issue 2, pp. 177-89, (2015) (PubMed).
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- 抗原
- Nephrin (NPHS1) (Nephrosis 1, Congenital, Finnish Type (Nephrin) (NPHS1))
- 别名
- Nephrin (NPHS1 产品)
- 别名
- NPHS1 antibody, nphs1l antibody, nphs1 antibody, CNF antibody, NPHN antibody, nephrin antibody, NephrinB antibody, NPHS1, nephrin antibody, nephrosis 1, congenital, Finnish type (nephrin) antibody, NPHS1 nephrin S homeolog antibody, nephrin antibody, NPHS1 nephrin antibody, nephrosis 1, nephrin antibody, NPHS1 antibody, nphs1 antibody, nphs1.S antibody, LOC5579127 antibody, Nphs1 antibody
- 背景
- Nephrin is strongly expressed in renal glomeruli and is a member of the immunoglobulin family of cell adhesion molecules. Mutations in the Nephrin gene result in congenital nephrotic syndrome, an autosomal-recessive disorder characterized by massive proteinuria in utero and nephrosis at birth. Renal glomeruli allow normal kidneys to filter plasma so that it is very pure. Nephrin is expressed in the podocyte slit-diaphragm of the renal glomeruli in a manner that suggests that Nephrin molecules homodimerize in an anti-parallel fashion similar to cadherin interactions in adherens junctions. Thus, Nephrin may constitute the entire extracellular structure of the slit-diaphragm. Despite its predicted molecular weight, Nephrin often migrates at a lower than expected size in SDS-PAGE.Synonyms: NPHN, NPHS1
- 基因ID
- 4868
- NCBI登录号
- NP_004637
- UniProt
- O60500
- 途径
- Regulation of Actin Filament Polymerization, Skeletal Muscle Fiber Development
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