SMURF1 抗体 (N-Term)
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- 抗原 See all SMURF1 抗体
- SMURF1 (SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1))
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抗原表位
- AA 180-230, N-Term
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SMURF1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- SMURF1 antibody is human, mouse and rat reactive. At least three isoforms of SMURF1 are known to exist this antibody will recognize all three isoforms. SMURF1 is predicted to not cross-react with SMURF2.
- 纯化方法
- SMURF1 antibody is affinity chromatography purified via peptide column.
- 免疫原
- SMURF1 antibody was raised against a 16 amino acid peptide near the amino terminus of human SMURF1. The immunogen is located within amino acids 180 - 230 of SMURF1.
- 亚型
- IgG
- Top Product
- Discover our top product SMURF1 Primary Antibody
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anti-SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1) (AA 165-268) antibody
SMURF1 适用: 人 WB, ELISA, IHC (p), IF, IP 宿主: 小鼠 Monoclonal 1D7 unconjugated
anti-SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1) (AA 198-374) antibodySMURF1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1) antibodySMURF1 适用: 人, 小鼠 WB, IHC (p), IF, EIA, IP 宿主: 小鼠 Monoclonal 1D7 unconjugated
anti-SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1) (AA 66-96), (N-Term) antibodySMURF1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB04101 unconjugated
anti-SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1) (AA 1-731) antibodySMURF1 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1) (AA 165-269) antibodySMURF1 适用: 人, 小鼠 WB, ELISA, IHC, IHC (p), IF, IP 宿主: 小鼠 Monoclonal 1D7 unconjugated
anti-SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1) (AA 66-96) antibodySMURF1 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1) (AA 711-740), (C-Term) antibodySMURF1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB4103 unconjugated
anti-SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1) (N-Term) antibodySMURF1 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1) (AA 165-268) antibodySMURF1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
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SMURF1 body can be used for detection of SMURF1 by Western blot at 1 - 2 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 5 μ,g/mL.
Antibody validated: Western Blot in human samples and Immunohistochemistry in rat samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- SMURF1 antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- SMURF1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- 抗原
- SMURF1 (SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1))
- 别名
- SMURF1 (SMURF1 产品)
- 别名
- 4930431E10Rik antibody, mKIAA1625 antibody, RGD1309707 antibody, SMAD specific E3 ubiquitin protein ligase 1 antibody, E3 ubiquitin-protein ligase SMURF1 antibody, SMAD specific E3 ubiquitin protein ligase 1 L homeolog antibody, SMURF1 antibody, LOC100540915 antibody, smurf1 antibody, Smurf1 antibody, smurf1.L antibody
- 背景
- SMURF1 (SMAD ubiquitin regulatory factor 1) is a negative regulator of TGF-beta signaling (1). SMURF1 and SMURF2 are members of HECT domain E3 ubiquitin ligase which are involved in the enzymatic reactions of the Ub conjugating pathway (1,2). SMURF1 negatively regulates osteoblast activity and response to bone morphogenesis protein (BMP) through controlling MEKK2 degradation (3). SMURF1 has recently been shown to play a role in breast cancer cell migration and invasion through the downregulation of RhoA (4).
- 分子量
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Predicted: 80, 83 kDa
Observed: 78 kDa - 基因ID
- 57154
- NCBI登录号
- NP_065162
- UniProt
- Q9HCE7
- 途径
- Regulation of Cell Size
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