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SMURF1 抗体 (AA 165-268)

This 小鼠 单克隆 antibody specifically detects SMURF1 in WB, ELISA, IF, IHC (p) 和 IP. It exhibits reactivity toward 人. It has been mentioned in 2+ publications
产品编号 ABIN566098
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for SMURF1 抗体 (AA 165-268) (ABIN566098)

抗原

See all SMURF1 抗体
SMURF1 (SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1))

适用

  • 65
  • 25
  • 14
人

宿主

  • 57
  • 9
小鼠

克隆类型

  • 58
  • 8
单克隆

标记

  • 28
  • 7
  • 5
  • 5
  • 5
  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SMURF1 antibody is un-conjugated

应用范围

  • 44
  • 31
  • 24
  • 12
  • 12
  • 7
  • 4
  • 3
  • 2
  • 1
  • 1
Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)

克隆位点

1D7
  • 抗原表位

    • 13
    • 9
    • 8
    • 7
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 165-268

    原理

    Mouse monoclonal antibody raised against a partial recombinant SMURF1.

    序列

    DSGPGRPLSC FMEEPAPYTD STGAAAGGGN CRFVESPSQD QRLQAQRLRN PDVRGSLQTP QNRPHGHQSP ELPEGYEQRT TVQGQVYFLH TQTGVSTWHD PRIP

    交叉反应

    人, 小鼠

    产品特性

    Antibody Reactive Against Recombinant Protein.

    免疫原

    SMURF1 (NP_065162, 165 a.a. ~ 268 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

    亚型

    IgG2a
  • 应用备注

    Suggested Applications*:elisa,immunoprecipitation,western blotting,immunohistochemistry (paraffin-embedded sections),immunofluorescence
    *We do not guarantee this product working for suggested applications.
    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    In 1x PBS, pH 7.4

    注意事项

    Aliquot to avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Wang, Zhang, Weng, Qiao, Ma, Xiao, Yu, Pan, Sun et al.: "Impaired phosphorylation and ubiquitination by p70 S6 kinase (p70S6K) and Smad ubiquitination regulatory factor 1 (Smurf1) promote tribbles homolog 2 (TRIB2) stability and carcinogenic property in ..." in: The Journal of biological chemistry, Vol. 288, Issue 47, pp. 33667-81, (2013) (PubMed).

    Murakami, Mathew, Huang, Farahani, Peng, Olson, Etlinger: "Smurf1 ubiquitin ligase causes downregulation of BMP receptors and is induced in monocrotaline and hypoxia models of pulmonary arterial hypertension." in: Experimental biology and medicine (Maywood, N.J.), Vol. 235, Issue 7, pp. 805-13, (2010) (PubMed).

  • 抗原

    SMURF1 (SMAD Specific E3 Ubiquitin Protein Ligase 1 (SMURF1))

    别名

    SMURF1

    背景

    Full Gene Name: SMAD specific E3 ubiquitin protein ligase 1
    Synonyms: KIAA1625

    基因ID

    57154

    NCBI登录号

    NM_020429

    途径

    Regulation of Cell Size
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