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TRPV4 抗体 (AA 380-430)

TRPV4 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6991967
发货至: 中国
  • 抗原 See all TRPV4 抗体
    TRPV4 (Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4))
    抗原表位
    • 16
    • 14
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 380-430
    适用
    • 59
    • 25
    • 24
    • 21
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 59
    • 2
    • 1
    • 1
    克隆类型
    • 62
    • 1
    多克隆
    标记
    • 29
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TRPV4 antibody is un-conjugated
    应用范围
    • 50
    • 24
    • 17
    • 14
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    特异性
    TRPV4 antibody is human specific. At least six isoforms of TRPV4 are known to exist. This antibody is predicted to not cross-react with other TRP protein family members.
    纯化方法
    TRPV4 antibody is affinity chromatography purified via peptide column.
    免疫原
    TRPV4 antibody was raised against an 18 amino acid peptide near the center of human TRPV4. The immunogen is located within amino acids 380 - 430 of TRPV4.
    亚型
    IgG
    Top Product
    Discover our top product TRPV4 Primary Antibody
  • 应用备注
    TRPV4 antibody can be used for detection of TRPV4 by Western blot at 1 μ,g/mL. Antibody can also be used for Immunohistochemistry starting at 2 μ,g/mL. For immunofluorescence start at 5 μ,g/mL.

    Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    TRPV4 antibody is supplied in PBS containing 0.02 % sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,4 °C
    储存方法
    TRPV4 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
  • 抗原
    TRPV4 (Transient Receptor Potential Cation Channel, Subfamily V, Member 4 (TRPV4))
    别名
    TRPV4 (TRPV4 产品)
    别名
    wu:fp52e02 antibody, CMT2C antibody, HMSN2C antibody, OTRPC4 antibody, SMAL antibody, SPSMA antibody, SSQTL1 antibody, TRP12 antibody, VRL2 antibody, VROAC antibody, 0610033B08Rik antibody, Trp12 antibody, VR-OAC antibody, VRL-2 antibody, Otrpc4 antibody, Vroac antibody, transient receptor potential cation channel, subfamily V, member 4 antibody, transient receptor potential cation channel subfamily V member 4 antibody, trpv4 antibody, TRPV4 antibody, Trpv4 antibody
    背景
    The transient receptor potential (TRP) protein family consists of a diverse group of cation channels functioning in a variety of homeostatic and regulatory pathways. Four subfamilies exist, based on channel domain homology: C type (canonical), V type (vanilloid receptor related), M type (melastatin related) and P type (PKD) (1). TRPV4, belongs to the V type subfamily and plays a role in systemic osmoregulation (2,3). TRPV4 is a calcium channel multi-pass membrane protein activated by various stimuli, including thermal stress, fatty acid metabolites and hypotonicity (3). TRPV4 is highly expressed in lung and kidney and widely expressed in brain. It plays an important role in regulating neural excitability (4).
    分子量
    Predicted: 96 kDa

    Observed: 100 kDa
    基因ID
    59341
    NCBI登录号
    NP_067638
    UniProt
    Q9HBA0
    途径
    Hormone Transport, Cell-Cell Junction Organization
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