PTRF 抗体 (C-Term)
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- 抗原 See all PTRF 抗体
- PTRF (Polymerase I and Transcript Release Factor (PTRF))
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抗原表位
- AA 270-320, C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PTRF antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- At least three isoforms of PTRF are known to exist, this antibody detects all three isoforms. It is predicted to not cross-react with other members of the cavin family.
- 纯化方法
- PTRF Antibody is affinity chromatography purified via peptide column.
- 免疫原
- Rabbit polyclonal PTRF antibody was raised against a 19 amino acid peptide near the carboxy terminus of human PTRF. The immunogen is located within amino acids 270 - 320 of PTRF.
- 亚型
- IgG
- Top Product
- Discover our top product PTRF Primary Antibody
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anti-Polymerase I and Transcript Release Factor (PTRF) (Middle Region) antibody
PTRF 适用: 人, 小鼠, 大鼠, Cow, 马, 兔, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Polymerase I and Transcript Release Factor (PTRF) (AA 233-321) antibodyPTRF 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Polymerase I and Transcript Release Factor (PTRF) (AA 1-390) antibodyPTRF 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Polymerase I and Transcript Release Factor (PTRF) (AA 1-390) antibodyPTRF 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Polymerase I and Transcript Release Factor (PTRF) (AA 233-321) antibodyPTRF 适用: 人 ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1F7 unconjugated
anti-Polymerase I and Transcript Release Factor (PTRF) (Internal Region) antibodyPTRF 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Polymerase I and Transcript Release Factor (PTRF) (AA 177-226) antibodyPTRF 适用: 人, 小鼠, Cow, 兔, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Polymerase I and Transcript Release Factor (PTRF) (AA 1-30) antibodyPTRF 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Polymerase I and Transcript Release Factor (PTRF) (AA 1-30), (N-Term) antibodyPTRF 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB15455 unconjugated
anti-Polymerase I and Transcript Release Factor (PTRF) (AA 12-44) antibodyPTRF 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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PTRF antibody can be used for detection of PTRF by Western blot at 0.5 - 1 μ,g/mL.
Antibody validated: Western Blot in human samples, Immunohistochemistry in human samples and Immunofluorescence in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PTRF Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- PTRF antibody can be stored at 4°C for three months and -20°C, stable for up to one year.
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- 抗原
- PTRF (Polymerase I and Transcript Release Factor (PTRF))
- 别名
- PTRF (PTRF 产品)
- 别名
- MGC53017 antibody, MGC89141 antibody, PTRF antibody, fd20g07 antibody, ptrf antibody, wu:fd20g07 antibody, zgc:162917 antibody, CAVIN antibody, CAVIN1 antibody, CGL4 antibody, cavin-1 antibody, 2310075E07Rik antibody, AW546441 antibody, Cav-p60 antibody, Cavin antibody, caveolae associated protein 1 L homeolog antibody, polymerase I and transcript release factor antibody, caveolae associated protein 1 antibody, caveolae associated protein 1b antibody, caveolae associated 1 antibody, cavin1.L antibody, PTRF antibody, cavin1 antibody, CAVIN1 antibody, cavin1b antibody, Cavin1 antibody
- 背景
- PTRF Antibody: The polymerase I and transcript release factor (PTRF) enables the dissociation of paused ternary polymerase I transcription complexes from the 3' end of pre-rRNA transcripts, regulating rRNA transcription by promoting the dissociation of transcription complexes and the re-initiation of polymerase I on nascent rRNA transcripts. PTRF also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins, translocating from caveolae to the cytoplasm after insulin stimulation. PTRF is also thought to modify lipid metabolism and insulin-regulated gene expression. Mutations in this gene result in a disorder characterized by generalized lipodystrophy and muscular dystrophy.
- 分子量
- 43 kDa
- 基因ID
- 284119
- NCBI登录号
- NP_036364
- UniProt
- Q6NZI2
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