ACVR1C/ALK7 抗体 (N-Term)
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- 抗原 See all ACVR1C/ALK7 (ACVR1C) 抗体
- ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))
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抗原表位
- AA 130-180, N-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ACVR1C/ALK7 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 特异性
- This antibody is predicted to have no cross-reactivity to ACVR1 or ACVR1B.
- 纯化方法
- ACVR1C Antibody is affinity chromatography purified via peptide column.
- 免疫原
- ACVR1C antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of the human ACVR1C. The immunogen is located within amino acids 130 - 180 of ACVR1C.
- 亚型
- IgG
- Top Product
- Discover our top product ACVR1C Primary Antibody
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anti-Activin Receptor Type 1C (ACVR1C) (AA 21-120) antibody
ACVR1C 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Activin Receptor Type 1C (ACVR1C) (AA 22-113) antibodyACVR1C 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Activin Receptor Type 1C (ACVR1C) antibodyACVR1C 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Activin Receptor Type 1C (ACVR1C) (Internal Region) antibodyACVR1C 适用: 人, Cow, Pig, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Activin Receptor Type 1C (ACVR1C) (N-Term) antibodyACVR1C 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Activin Receptor Type 1C (ACVR1C) antibodyACVR1C 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Activin Receptor Type 1C (ACVR1C) (C-Term) antibodyACVR1C 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Activin Receptor Type 1C (ACVR1C) (Center) antibodyACVR1C 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Activin Receptor Type 1C (ACVR1C) (AA 21-493) antibodyACVR1C 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Activin Receptor Type 1C (ACVR1C) (AA 33-62), (N-Term) antibodyACVR1C 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB8195 unconjugated
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- 应用备注
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ACVR1C antibody can be used for detection of ACVR1C by Western blot at 1 and 2 μ,g/mL.
Antibody validated: Western Blot in human samples. All other applications and species not yet tested. - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- ACVR1C Antibody is supplied in PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,4 °C
- 储存方法
- ACVR1C antibody can be stored at 4°C for three months and -20°C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
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- 抗原
- ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))
- 别名
- ACVR1C (ACVR1C 产品)
- 别名
- ACVRLK7 antibody, ALK7 antibody, Alk-7 antibody, C230097P10 antibody, Alk7 antibody, habrec1 antibody, activin A receptor type 1C antibody, activin A receptor, type IC antibody, ACVR1C antibody, Acvr1c antibody
- 背景
- ACVR1C Antibody: Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. ACVR1C, also known as ALK7, is a type I activin receptor and plays a role in cell differentiation, growth arrest and apoptosis. ACVR1C can mediate signaling by ligans such as Nodal, GDF-1/3, activin B and activin AB, all of which can also signal through the ubiquitous activin type I receptor ACVR1B (also known as ALK4). ACVR1C is a novel marker specifically expressed during the late phase of adipocyte differentiation. ACVR1C is dispensable for mouse embryogenesis, which suggests alternative functions for this receptor in postnatal development and tissue homeostasis. ACVR1C plays an important role in regulating the functional plasticity of pancreatic islets, negatively affecting beta-cell function by mediating the effects of activin B on Ca2+ signaling.
- 基因ID
- 90
- UniProt
- Q04771, Q8NER5
- 途径
- Negative Regulation of Hormone Secretion, Positive Regulation of Endopeptidase Activity
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