ACVR1C/ALK7 抗体 (N-Term)
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- 抗原 See all ACVR1C/ALK7 (ACVR1C) 抗体
- ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))
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抗原表位
- AA 33-62, N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ACVR1C/ALK7 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 预测反应
- M
- 纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- 免疫原
- This Activin A Receptor Type IC (ACVR1C) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-62 amino acids from the N-terminal region of human Activin A Receptor Type IC (ACVR1C).
- 克隆位点
- RB8195
- 亚型
- Ig Fraction
- Top Product
- Discover our top product ACVR1C Primary Antibody
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anti-Activin Receptor Type 1C (ACVR1C) (AA 21-120) antibody
ACVR1C 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Activin Receptor Type 1C (ACVR1C) (AA 22-113) antibodyACVR1C 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Activin Receptor Type 1C (ACVR1C) antibodyACVR1C 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Activin Receptor Type 1C (ACVR1C) (Internal Region) antibodyACVR1C 适用: 人, Cow, Pig, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Activin Receptor Type 1C (ACVR1C) (N-Term) antibodyACVR1C 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Activin Receptor Type 1C (ACVR1C) antibodyACVR1C 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Activin Receptor Type 1C (ACVR1C) (C-Term) antibodyACVR1C 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Activin Receptor Type 1C (ACVR1C) (Center) antibodyACVR1C 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Activin Receptor Type 1C (ACVR1C) (AA 21-493) antibodyACVR1C 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Activin Receptor Type 1C (ACVR1C) (AA 72-121) antibodyACVR1C 适用: 人, 大鼠, Cow, 兔, 豚鼠, 马, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000. IHC-P: 1:50~100
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
- 有效期
- 6 months
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: "Overexpression of B2M and loss of ALK7 expression are associated with invasion, metastasis, and poor-prognosis of the pancreatic ductal adenocarcinoma." in: Cancer biomarkers : section A of Disease markers, Vol. 15, Issue 6, pp. 735-43, (2015) (PubMed).
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: "Overexpression of B2M and loss of ALK7 expression are associated with invasion, metastasis, and poor-prognosis of the pancreatic ductal adenocarcinoma." in: Cancer biomarkers : section A of Disease markers, Vol. 15, Issue 6, pp. 735-43, (2015) (PubMed).
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- 抗原
- ACVR1C/ALK7 (ACVR1C) (Activin Receptor Type 1C (ACVR1C))
- 别名
- Activin A Receptor Type IC (ACVR1C) (ACVR1C 产品)
- 别名
- ACVRLK7 antibody, ALK7 antibody, Alk-7 antibody, C230097P10 antibody, Alk7 antibody, habrec1 antibody, activin A receptor type 1C antibody, activin A receptor, type IC antibody, ACVR1C antibody, Acvr1c antibody
- 背景
- ACVR1C, a serine/threonine protein kinase, is a type I receptor for the TGFB family of signaling molecules. The receptor complex consisting of 2 type II and 2 type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators, SMAD2 and SMAD3, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors. ACVR1C is a receptor for activin AB, activin B and NODAL. This protein plays a role in cell differentiation, growth arrest and apoptosis.
- 分子量
- 54871
- 基因ID
- 130399
- NCBI登录号
- NP_001104501, NP_001104502, NP_001104503, NP_660302
- UniProt
- Q8NER5
- 途径
- Negative Regulation of Hormone Secretion, Positive Regulation of Endopeptidase Activity
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