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CHEK1 抗体 (pSer296)

This anti-CHEK1 antibody is a 兔 单克隆 antibody detecting CHEK1 in WB, IHC 和 IHC (p). Suitable for 人.
产品编号 ABIN6989950
发货至: 中国

Quick Overview for CHEK1 抗体 (pSer296) (ABIN6989950)

抗原

See all CHEK1 抗体
CHEK1 (Checkpoint Kinase 1 (CHEK1))

适用

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宿主

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克隆类型

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单克隆

标记

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This CHEK1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

4B6
  • 抗原表位

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    pSer296

    交叉反应

    纯化方法

    Purified by Protein A.

    免疫原

    Synthetic phospho-Peptide corresponding to residues surrounding Ser296 of human Chk1

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC()

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    CHEK1 (Checkpoint Kinase 1 (CHEK1))

    别名

    Chk1

    背景

    Synonyms: C85740 antibody, Cell cycle checkpoint kinase antibody, Checkpoint , S. pombe, homolog of, 1 antibody, Checkpoint kinase 1 antibody, Checkpoint kinase 1 homolog (S. pombe) antibody, CHEK 1 antibody, Chek1 antibody, Chk 1 antibody, Chk1 antibody, CHK1 checkpoint homolog (S. pombe) antibody, CHK1_HUMAN antibody, EC 2.7.11.1 antibody, rad27 antibody, Serine/threonine protein kinase Chk1 antibody, Serine/threonine-protein kinase CHK1 antibody, STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae) antibody

    Background: The protein encoded by this gene belongs to the Ser/Thr protein kinase family. It is required for checkpoint mediated cell cycle arrest in response to DNA damage or the presence of unreplicated DNA. This protein acts to integrate signals from ATM and ATR, two cell cycle proteins involved in DNA damage responses, that also associate with chromatin in meiotic prophase I. Phosphorylation of CDC25A protein phosphatase by this protein is required for cells to delay cell cycle progression in response to double-strand DNA breaks. Several alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Oct 2011].

    基因ID

    1111

    UniProt

    O14757

    途径

    p53 Pathway, Apoptosis, Cell Division Cycle, DNA Damage Repair
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