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CD45 抗体 (AA 1-100)

Name: CD45 抗体 (AA 1-100)
SKU: ABIN6989429
Availability: OutOfStock

PTPRC 适用: 人 FACS, WB, IHC (p), ELISA, IHC (fro) 宿主: 小鼠 Monoclonal 14A9 unconjugated

产品编号 ABIN6989429

发货至: 中国

Datasheet as PDF

抗原 See all CD45 (PTPRC) 抗体

CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))
抗原表位
16

16

14

13

12

10

9

7

6

6

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-100
适用
347

208

79

29

20

16

15

10

7

6

6

4

4

3

3

3

2

1

1

1

1

1

1
人
宿主
246

160

137

2

1
小鼠
Compatible Secondaries
克隆类型
410

128

1
单克隆
标记
163

52

44

43

34

13

12

11

10

9

8

8

8

6

6

6

6

6

6

5

4

4

4

4

4

4

4

4

4

4

4

4

3

3

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1
This CD45 antibody is un-conjugated
应用范围
443

185

147

120

91

57

42

38

38

27

15

14

13

12

9

5

4

3

3

2

2

1

1

1

1

1

1
Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))

交叉反应

人

纯化方法

Purified by Protein G.

免疫原

Recombinant human CD45

克隆位点

14A9

亚型

IgG1

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anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (C-Term) antibody
PTPRC 适用: 人, 小鼠, 大鼠, 犬, 小鸡, Cow, Cat, 兔, 绵羊, Pig, 豚鼠, 山羊, 马, 猴, Hamster, 驴, Avian WB 宿主: 山羊 Polyclonal unconjugated

anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) antibody
PTPRC 适用: 人 FACS, IHC, WB, IF, StM 宿主: 兔 Monoclonal PTPRC-2877R unconjugated Recombinant Antibody

anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) antibody
PTPRC 适用: 人 FACS, WB, IP, IHC (p), ICC 宿主: 小鼠 Monoclonal MEM-28 unconjugated

anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 378-577) antibody
PTPRC 适用: 人, 小鼠, 大鼠 FACS, IHC, WB, ELISA, ICC 宿主: 小鼠 Monoclonal 2H3E2 unconjugated

anti-Protein tyrosine Phosphatase, Receptor Type, C (PTPRC) (AA 431-577) antibody
PTPRC 适用: 人 FACS, IHC, WB, ELISA, ICC, Neut 宿主: 小鼠 Monoclonal 7C9F12 unconjugated

应用备注

WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

有效期

12 months
抗原

CD45 (PTPRC) (Protein tyrosine Phosphatase, Receptor Type, C (PTPRC))

别名

CD45 (PTPRC 产品)

别名

PTPRC antibody, si:dkeyp-47c5.1 antibody, B220 antibody, CD45 antibody, CD45R antibody, GP180 antibody, L-CA antibody, LCA antibody, LY5 antibody, T200 antibody, Cd45 antibody, Ly-5 antibody, Lyt-4 antibody, loc antibody, Lca antibody, RT7 antibody, cd45 antibody, protein tyrosine phosphatase, receptor type C antibody, protein tyrosine phosphatase, receptor type, C antibody, receptor-type tyrosine-protein phosphatase C antibody, PTPRC antibody, ptprc antibody, LOC100074271 antibody, Ptprc antibody

背景

Synonyms: B220, CD 45, CD-45, CD45, cd45 antigen, ec3.1.3.48, CD45R, GP180, GP180, GP 180, L CA, LCA, L-CA, Leukocyte common antigen, LY5, Ly-5 glycoprotein, Protein tyrosine phosphatase receptor type C, Protein tyrosine phosphatase receptor type c polypeptide, protein tyrosine phosphatase, receptor type, C, Receptor-type tyrosine-protein phosphatase C, PTPRC, PTPRC_HUMAN, SCID due to PTPRC deficiency, T200, T200 glycoprotein, T200 leukocyte common antigen, Human homolog of severe combined immunodeficiency due to PTPRC deficiency.
Background: Protein tyrosine-protein phosphatase required for T-cell activation through the antigen receptor. Acts as a positive regulator of T-cell coactivation upon binding to DPP4. The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one. Upon T-cell activation, recruits and dephosphorylates SKAP1 and FYN. Dephosphorylates LYN, and thereby modulates LYN activity.

基因ID

5788

UniProt

P08575

途径

TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, CXCR4-mediated Signaling Events, BCR Signaling