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MCM2 抗体 (pSer53)

This anti-MCM2 antibody is a 兔 多克隆 antibody detecting MCM2 in ELISA, IHC (p), ICC, IF (p), IF (cc) 和 IHC (fro). Suitable for 人.
产品编号 ABIN6989144
发货至: 中国

Quick Overview for MCM2 抗体 (pSer53) (ABIN6989144)

抗原

See all MCM2 抗体
MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))

适用

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宿主

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克隆类型

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多克隆

标记

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This MCM2 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Frozen Sections) (IHC (fro))
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    pSer53

    交叉反应

    预测反应

    Mouse,Rat,Dog,Sheep,Pig,Horse,Chicken,Rabbit,Zebrafish

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated Synthesised phosphopeptide derived from human MCM2 around the phosphorylation site of Ser53

    亚型

    IgG
  • 应用备注

    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

    有效期

    12 months
  • 抗原

    MCM2 (Minichromosome Maintenance Complex Component 2 (MCM2))

    别名

    MCM2

    背景

    Synonyms: MCM4 (phospho S53), MCM2(phospho-Ser53), MCM2(phospho Ser53), MCM2 (phospho S54), p-MCM2(Ser53), p-MCM2(S53), rat MCM4 (phospho S54), BM28, CCNL 1, CCNL1, CDC like 1, CDC like-1, cdc19, CDCL 1, CDCL1, Cell devision cycle like 1, Cyclin like 1, cyclin like-1, D3S3194, DNA replication licensing factor MCM2, KIAA0030, MCM 2, MCM2, MCM2 minichromosome maintenance deficient 2 mitotin, MCM2 minichromosome maintenance deficient 2 mitotin (S. cerevisiae), MCM2 minichromosome maintenance deficient 2, mitotin, MCM2_HUMAN, MCM2_MOUSE, MGC10606, Minichromosome maintenance complex component 2, Minichromosome maintenance deficient 2 (mitotin), Minichromosome maintenance deficient 2 mitotin, Minichromosome maintenance protein 2, Minichromosome maintenance protein 2 homolog, Mitotin, Nuclear protein BM28, OTTHUMP00000216047, OTTHUMP00000216050.

    Background: Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division.

    基因ID

    4171

    UniProt

    P49736

    途径

    DNA Damage Repair, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA
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