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- 抗原 See all IL-1 beta (IL1B) 抗体
- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This IL-1 beta antibody is conjugated to Biotin
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应用范围
- ELISA, ELISpot
- 特异性
- Native and recombinant human IL-1β. The antibody binds to the pro-form and active form of IL-1β. No cross-reactivity with IL-1α.
- 交叉反应 (详细)
- This monoclonal antibody enables sensitive and specific detection of human IL-1β in immunoassays such as ELISA and ELISpot. The antibody binds to the pro-form and the active form of IL-1β. It does not cross-react with IL-1α.
- 产品特性
- This monoclonal antibody enables specific detection of human IL-1β in immunoassays such as ELISpot, FluoroSpot, and ELISA. Serum/Plasma samples
- 纯化方法
- Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.,Purified from in vitro cultures by protein G affinity chromatography.
- 过滤
- 0.2 μm filtered
- 免疫原
- Recombinant human IL-1beta
- 克隆位点
- 7P10
- 亚型
- IgG2b
- Top Product
- Discover our top product IL1B Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 说明
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ABIN6963832 and ABIN7448283 is recommended as detection mAb in ELISpot, FluoroSpot, and ELISA in combination with capture mAb ABIN6963831 and ABIN7448282 .
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.5 mg/mL
- 缓冲液
- supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.
- 有效期
- 18 months
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Curcumin reduces the expression of interleukin 1β and the production of interleukin 6 and tumor necrosis factor alpha by M1 macrophages from patients with Behcet's disease." in: Immunopharmacology and immunotoxicology, Vol. 40, Issue 4, pp. 297-302, (2018) (PubMed).
: "Macrophage migration inhibitory factor is required for NLRP3 inflammasome activation." in: Nature communications, Vol. 9, Issue 1, pp. 2223, (2018) (PubMed).
: "Innate immune responses following Kawasaki disease and toxic shock syndrome." in: PLoS ONE, Vol. 13, Issue 2, pp. e0191830, (2018) (PubMed).
: "Circulating monocytes are not the major source of plasma cytokines in patients with sepsis." in: Shock (Augusta, Ga.), Vol. 38, Issue 6, pp. 577-83, (2013) (PubMed).
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Curcumin reduces the expression of interleukin 1β and the production of interleukin 6 and tumor necrosis factor alpha by M1 macrophages from patients with Behcet's disease." in: Immunopharmacology and immunotoxicology, Vol. 40, Issue 4, pp. 297-302, (2018) (PubMed).
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- 抗原
- IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
- 别名
- IL1B (IL1B 产品)
- 基因ID
- 3553
- 途径
- NF-kappaB Signaling, Interferon-gamma Pathway, TLR signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome
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