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IL-1 beta 抗体 (Biotin)

IL1B 适用: 人 ELISA, ELISpot 宿主: 小鼠 Monoclonal 7P10 Biotin
产品编号 ABIN6963832
发货至: 中国
  • 抗原 See all IL-1 beta (IL1B) 抗体
    IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
    适用
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    小鼠
    克隆类型
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    单克隆
    标记
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    This IL-1 beta antibody is conjugated to Biotin
    应用范围
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    ELISA, ELISpot
    特异性
    Native and recombinant human IL-1β. The antibody binds to the pro-form and active form of IL-1β. No cross-reactivity with IL-1α.
    交叉反应 (详细)
    This monoclonal antibody enables sensitive and specific detection of human IL-1β in immunoassays such as ELISA and ELISpot. The antibody binds to the pro-form and the active form of IL-1β. It does not cross-react with IL-1α.
    产品特性
    This monoclonal antibody enables specific detection of human IL-1β in immunoassays such as ELISpot, FluoroSpot, and ELISA. Serum/Plasma samples
    纯化方法
    Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.,Purified from in vitro cultures by protein G affinity chromatography.
    过滤
    0.2 μm filtered
    免疫原
    Recombinant human IL-1beta
    克隆位点
    7P10
    亚型
    IgG2b
    Top Product
    Discover our top product IL1B Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    说明

    ABIN6963832 and ABIN7448283 is recommended as detection mAb in ELISpot, FluoroSpot, and ELISA in combination with capture mAb ABIN6963831 and ABIN7448282 .

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.5 mg/mL
    缓冲液
    supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.
    有效期
    18 months
  • Palizgir, Akhtari, Mahmoudi, Mostafaei, Rezaiemanesh, Shahram: "Curcumin reduces the expression of interleukin 1β and the production of interleukin 6 and tumor necrosis factor alpha by M1 macrophages from patients with Behcet's disease." in: Immunopharmacology and immunotoxicology, Vol. 40, Issue 4, pp. 297-302, (2018) (PubMed).

    Lang, Lee, Elgass, Pinar, Tate, Aitken, Fan, Creed, Deen, Traore, Mueller, Stanisic, Baiwog, Skene, Wilce, Mansell, Morand, Harris: "Macrophage migration inhibitory factor is required for NLRP3 inflammasome activation." in: Nature communications, Vol. 9, Issue 1, pp. 2223, (2018) (PubMed).

    Chen, Messina, Germano, Bonnici, Freyne, Cheung, Goldsmith, Kollmann, Levin, Burgner, Curtis: "Innate immune responses following Kawasaki disease and toxic shock syndrome." in: PLoS ONE, Vol. 13, Issue 2, pp. e0191830, (2018) (PubMed).

    Gille-Johnson, Smedman, Gudmundsdotter, Somell, Nihlmark, Paulie, Andersson, Gårdlund: "Circulating monocytes are not the major source of plasma cytokines in patients with sepsis." in: Shock (Augusta, Ga.), Vol. 38, Issue 6, pp. 577-83, (2013) (PubMed).

  • 抗原
    IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))
    别名
    IL1B (IL1B 产品)
    基因ID
    3553
    途径
    NF-kappaB Signaling, Interferon-gamma Pathway, TLR signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome
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