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TNFRSF18 抗体 (PE)

TNFRSF18 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal DTA-1 PE
产品编号 ABIN6961553
发货至: 中国
  • 抗原 See all TNFRSF18 抗体
    TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))
    适用
    • 56
    • 29
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    小鼠
    宿主
    • 33
    • 25
    • 24
    大鼠
    克隆类型
    • 49
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    单克隆
    标记
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    This TNFRSF18 antibody is conjugated to PE
    应用范围
    • 40
    • 33
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    Flow Cytometry (FACS)
    纯化方法
    This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. It is recommended to store the product undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.
    克隆位点
    DTA-1
    亚型
    IgG2b
    Top Product
    Discover our top product TNFRSF18 Primary Antibody
  • 应用备注
    This antibody preparation has been quality-tested for flow cytometry using mouse spleen cells, or an appropriate cell type (where indi- cated). The amount of antibody required for optimal staining of a cell sample should be determined empirically in your system.
    说明

    0.2 mg/mL

    限制
    仅限研究用
  • 缓冲液
    10 mM NaH2PO4, 150 mM NaCl, 0.05 % BSA, 0.05 % Sodium azide, pH 7.2
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    2-8°C protected from light
    有效期
    12 months
  • 抗原
    TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))
    别名
    CD357 (GITR) (TNFRSF18 产品)
    别名
    GITR antibody, TNFRSF18 antibody, AITR antibody, Gitr antibody, CD357 antibody, GITR-D antibody, TNF receptor superfamily member 18 antibody, tumor necrosis factor receptor superfamily, member 18 antibody, TNFRSF18 antibody, Tnfrsf18 antibody
    背景
    The DTA-1 antibody reacts with mouse CD357, also known as GITR or AITR (in humans), a 66-70 kDa member of the Tumor Necrosis Factor superfamily (TNFRSF18). GITR is primarily found on T cells, and its function may vary depending on the T cell type where it is ex- pressed. GITR is upregulated on activated T cells where it provides co-stimulation, yet GITR may promote the inhibition of CD4+ CD25+ Treg cells, where it is expressed at high levels. GITR ligand (GITRL) is found on B cells, macrophages, dendritic and endothelial cells, and is implicated in regulating both innate and adaptive immune responses.The DTA-1 antibody may be used for analysis of GITR expres- sion on T cells, and is also commonly used in vitro as an agonistic antibody to induce GITR signaling in various assays.
    基因ID
    21936
    UniProt
    O35714
    途径
    Cancer Immune Checkpoints
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