TNFRSF18 抗体 (AA 184-241)
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- 抗原 See all TNFRSF18 抗体
- TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))
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抗原表位
- AA 184-241
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TNFRSF18 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Neutralization (Neut)
- 纯化方法
- purified
- 免疫原
- Purified recombinant fragment of human GITR (AA: 184-241) expressed in E. coli.
- 克隆位点
- 6H8B9
- 亚型
- IgG1
- Top Product
- Discover our top product TNFRSF18 Primary Antibody
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- 应用备注
- ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400, ICC: N/A, IHC: N/A
- 限制
- 仅限研究用
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- 缓冲液
- Purified antibody in PBS with 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- 4°C, -20°C for long term storage
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- 抗原
- TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))
- 别名
- GITR (TNFRSF18 产品)
- 别名
- GITR antibody, TNFRSF18 antibody, AITR antibody, Gitr antibody, CD357 antibody, GITR-D antibody, TNF receptor superfamily member 18 antibody, tumor necrosis factor receptor superfamily, member 18 antibody, TNFRSF18 antibody, Tnfrsf18 antibody
- 背景
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Description: This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
Aliases: TNFRSF18, AITR, CD357, GITR-D
- 分子量
- 26 kDa
- 基因ID
- 8784
- 途径
- Cancer Immune Checkpoints
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