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YBX1 抗体

YBX1 适用: 人, 大鼠, 小鼠 WB, IHC, IHC (p), IF (cc), FACS 宿主: 兔 Monoclonal 2B12 unconjugated
产品编号 ABIN6945400
发货至: 中国
  • 抗原 See all YBX1 抗体
    YBX1 (Y Box Binding Protein 1 (YBX1))
    适用
    • 111
    • 75
    • 62
    • 21
    • 19
    • 18
    • 17
    • 7
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    • 6
    • 5
    • 5
    • 5
    • 2
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 102
    • 11
    克隆类型
    • 95
    • 18
    单克隆
    标记
    • 54
    • 7
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    • 6
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    • 5
    • 5
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    • 2
    • 2
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    • 2
    • 2
    • 1
    • 1
    This YBX1 antibody is un-conjugated
    应用范围
    • 79
    • 24
    • 15
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    • 13
    • 13
    • 11
    • 6
    • 4
    • 2
    • 2
    • 2
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    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Flow Cytometry (FACS)
    交叉反应
    人, 小鼠, 大鼠
    纯化方法
    Purified by Protein A.
    免疫原
    Human YB1 aa 250 to the C-terminus
    克隆位点
    2B12
    亚型
    IgG
    Top Product
    Discover our top product YBX1 Primary Antibody
  • 应用备注
    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(ICC) 1:50-200
    IHC()
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C for 12 months.
    有效期
    12 months
  • 抗原
    YBX1 (Y Box Binding Protein 1 (YBX1))
    别名
    YB1 (YBX1 产品)
    别名
    BP-8 antibody, CSDA2 antibody, CSDB antibody, DBPB antibody, MDR-NF1 antibody, NSEP-1 antibody, NSEP1 antibody, YB-1 antibody, YB1 antibody, Byb1 antibody, Cbfa antibody, Dbpb antibody, Ef1a antibody, Msy1 antibody, Nsep1 antibody, Yb1 antibody, bp-8 antibody, csda2 antibody, csdb antibody, dbpb antibody, frgy1 antibody, mdr-nf1 antibody, nsep-1 antibody, nsep1 antibody, yb1 antibody, 1700102N10Rik antibody, C79409 antibody, EF1A antibody, MSY1 antibody, dbpB antibody, mYB-1a antibody, nuclease sensitive element binding protein 1 antibody, Y-box binding protein 1 antibody, Y box binding protein 1 antibody, Y-box binding protein 1 S homeolog antibody, nuclease-sensitive element-binding protein 1 antibody, Y box protein 1 antibody, nsep1 antibody, YBX1 antibody, Ybx1 antibody, ybx1.S antibody, LOC479011 antibody
    背景

    Synonyms: Nuclease-sensitive element-binding protein 1, CCAAT-binding transcription factor I subunit A, DNA-binding protein B, Enhancer factor I subunit A, Y-box transcription factor, Y-box-binding protein 1, CBF-A, DBPB, EFI-A, YB-1, YBX1

    Background: Mediates pre-mRNA alternative splicing regulation. Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors (By similarity). Regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). May play a role in DNA repair. Component of the CRD-mediated complex that promotes MYC mRNA stability. Binds preferentially to the 5'-[CU]CUGCG-3' motif in vitro. The secreted form acts as an extracellular mitogen and stimulates cell migration and proliferation.

    基因ID
    4904
    UniProt
    P67809
    途径
    Regulation of Muscle Cell Differentiation
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