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CD4 抗体

CD4 适用: 小鼠 FACS, ELISA, IF, Coat, Neut 宿主: 大鼠 Monoclonal GK1-5 unconjugated
产品编号 ABIN6933685
发货至: 中国
  • 抗原 See all CD4 抗体
    CD4
    适用
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    小鼠
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    大鼠
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    单克隆
    标记
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    This CD4 antibody is un-conjugated
    应用范围
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    Flow Cytometry (FACS), ELISA, Immunofluorescence (IF), Coating (Coat), Neutralization (Neut)
    无交叉反应
    纯化方法
    Purified by Protein A/G
    免疫原
    Mouse CTL clone V4
    克隆位点
    GK1-5
    亚型
    IgG2b kappa
    Top Product
    Discover our top product CD4 Primary Antibody
  • 应用备注

    Positive Control: Spleen, Thymus or Lymph Node.

    Known Application: ELISA (For coating, order Ab without BSA & Azide), Neutralization Studies (Order Ab without BSA & Azide), Flow Cytometry (0.5-1 μg/million cells), Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    10 mM PBS with 0.05 % BSA & 0.05 % azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-80 °C
    储存方法
    Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
    有效期
    24 months
  • 抗原
    CD4
    别名
    CD4 (T-Cell Marker) (CD4 产品)
    别名
    cd4 antibody, L3T4 antibody, Ly-4 antibody, CD4mut antibody, W3/25 antibody, p55 antibody, CD4 molecule antibody, carcinoembryonic antigen-related cell adhesion molecule 5 antibody, T-cell surface glycoprotein CD4 antibody, CD4 antigen antibody, Cd4 molecule antibody, CD4 antibody, LOC100125525 antibody, cd4 antibody, Cd4 antibody
    背景
    CD4 is a member of the Ig superfamily, primarily expressed on most thymocytes, a subset of T cells, and weakly on macrophages and dendritic cells. It acts as a coreceptor with the TCR during T cell activation and thymic differentiation by binding MHC class II and associating with the protein tyrosine kinase, lck. CD4 is expressed by the majority of thymocytes, most helper T cells, a subset of NK-T cells and weakly by dendritic cells and macrophages. CD4 plays an important role in the development of T cells and is required for mature T cells to function optimally.This antibody blocks helper T cell responses to MHC class II antigens, including cytolysis, proliferation, allogeneic B cell help, and release of lymphokines.
    分子量
    55kDa
    基因ID
    12504
    UniProt
    P06332
    途径
    TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events
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