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- 抗原 See all TNFRSF18 抗体
- TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This TNFRSF18 antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunofluorescence (IF)
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Mouse CD25+ CD4+ T cells
- 克隆位点
- DTA-1
- 亚型
- IgG2b kappa
- Top Product
- Discover our top product TNFRSF18 Primary Antibody
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 26-162) antibody
TNFRSF18 适用: 人 FACS, ELISA, WB, IHC, ICC, Neut 宿主: 小鼠 Monoclonal 2A7A6 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 266-162) antibodyTNFRSF18 适用: 人 FACS, ELISA 宿主: 兔 Monoclonal DM78 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 201-274) antibodyTNFRSF18 适用: 人 ELISA, IF (p), IF (cc), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 184-241) antibodyTNFRSF18 适用: 人 FACS, ELISA, WB, IHC, ICC, Neut 宿主: 小鼠 Monoclonal 6H8B9 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 90-162) antibodyTNFRSF18 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 1-241) antibodyTNFRSF18 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 26-115) antibodyTNFRSF18 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2H4 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (C-Term) antibodyTNFRSF18 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 50-177) antibodyTNFRSF18 适用: 人 FACS, ELISA 宿主: 兔 Monoclonal DM52 unconjugated Recombinant Antibody
anti-Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18) (AA 26-115) antibodyTNFRSF18 适用: 人, 小鼠 ELISA, WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2H4 unconjugated
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- 应用备注
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Positive Control: CD25+CD4+Tregs.
Known Application: Flow Cytometry (0.5-1 μg/million cells in 0.1ml), Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))
- 别名
- GITR / Tnfrsf18 (TNFRSF18 产品)
- 别名
- GITR antibody, TNFRSF18 antibody, AITR antibody, Gitr antibody, CD357 antibody, GITR-D antibody, TNF receptor superfamily member 18 antibody, tumor necrosis factor receptor superfamily, member 18 antibody, TNFRSF18 antibody, Tnfrsf18 antibody
- 背景
- GITR (glucocorticoid-induced TNFR-related gene) is a member of the TNF-receptor superfamily, also known as TNFRSF18. It is expressed at low levels on resting T lymphocytes and at high levels on CD25+CD4+Tregs. The expression of GITR on T cells can be upregulated upon activation. Interaction of GITR with its ligand (GITRL) has been demonstrated to augment T cell activation, proliferation, cytokine production as well as MAPKs and NF-B activation, and abrogate the inhibitory function ofCD25+CD4+Tregs. In vivoactivation of GITR causes development of autoimmune diseases and restores the suppressed immune response.
- 分子量
- 66-70kDa (Homodimer)
- 基因ID
- 21936
- UniProt
- O35714
- 途径
- Cancer Immune Checkpoints
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