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- 抗原 See all ROR2 抗体
- ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This ROR2 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Staining Methods (StM)
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Human cultured keratinocytes
- 克隆位点
- ROR2-1911
- 亚型
- IgG
- Top Product
- Discover our top product ROR2 Primary Antibody
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anti-Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 683-934) antibody
ROR2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 59-155) antibodyROR2 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 6F2D10 unconjugated
anti-Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 19-50), (N-Term) antibodyROR2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB01507-01508 unconjugated
anti-Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 19-50) antibodyROR2 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 752-926) antibodyROR2 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 915-943), (C-Term) antibodyROR2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB01510 unconjugated
anti-Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 100-200) antibody (FITC)ROR2 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal FITC
anti-Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 100-200) antibody (Alkaline Phosphatase (AP))ROR2 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal Alkaline Phosphatase (AP)
anti-Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 100-200) antibody (Biotin)ROR2 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal Biotin
anti-Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2) (AA 100-200) antibody (APC)ROR2 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal APC
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- 应用备注
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Positive Control: Human breast, pancreas, kidney or GIST.
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- ROR2 (Receptor Tyrosine Kinase-Like Orphan Receptor 2 (ROR2))
- 别名
- ROR2 (ROR2 产品)
- 别名
- BDB antibody, BDB1 antibody, NTRKR2 antibody, Ntrkr2 antibody, mRor2 antibody, ROR2 antibody, bdb antibody, bdb1 antibody, Xror2 antibody, ntrkr2 antibody, MGC97773 antibody, LOC100219935 antibody, ror2 antibody, xror2 antibody, receptor tyrosine kinase like orphan receptor 2 antibody, receptor tyrosine kinase-like orphan receptor 2 antibody, receptor tyrosine kinase like orphan receptor 2 L homeolog antibody, ROR2 antibody, Ror2 antibody, ror2 antibody, ror2.L antibody
- 背景
- ROR2 (receptor tyrosine kinase-like orphan receptor 2), also known as neurotrophic tyrosine kinase receptor-related 2 (NTRKR2), is a single pass transmembrane tyrosine-protein kinase receptor. It contains a cytoplasmic tyrosine kinase domain, distally located serine-threonine-rich domains, an extracellular immunoglobulin-like domain, a cysteine-rich domain and a kringle domain. ROR2 is important for skeletal and endocrine development and is required for cartilage and growth plate development. It promotes the differentiation of osteoblasts and plays an important role in the early formation of chondrocytes. ROR2 sequesters and associates with Dlxin-1 affecting the transcriptional function of Msx-2. ROR2 also interacts with canoncial Wnt-1 and Wnt-3, regulating their signaling pathways. Defects in ROR2 can result in the autosomal dominant skeletal disorder, brachydactyly type B1, or the autosomal recessive skeletal disorder, Robinow syndrome.
- 分子量
- 120kDa
- 基因ID
- 4920
- UniProt
- Q01974
- 途径
- RTK signaling, WNT signaling
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