XRCC6/XRCC5 抗体
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- 抗原 See all XRCC6/XRCC5 products
- XRCC6/XRCC5 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5/6 (XRCC6/XRCC5))
- 适用
- 人, 灵长类
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This XRCC6/XRCC5 antibody is un-conjugated
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应用范围
- Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)
- 特异性
- Recognizes a dimer of two proteins of 70 kDa and ~80 kDa, identified as two subunits of Ku. This MAb recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460 kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.
- 无交叉反应
- 小鸡, 小鼠, 大鼠
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Nuclear extract of human HL-60 cells
- 克隆位点
- KU729
- 亚型
- IgG1 kappa
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anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5/6 (XRCC6/XRCC5) (AA 683-732) antibody
XRCC6/XRCC5 适用: 人 IF, IHC, IHC (p), WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5/6 (XRCC6/XRCC5) antibody (PE)XRCC6/XRCC5 适用: 人, 灵长类 IF, FACS, T 宿主: 小鼠 Monoclonal KU729 PE
anti-X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5/6 (XRCC6/XRCC5) antibody (CF®488A)XRCC6/XRCC5 适用: 人, 灵长类 IF, FACS, T 宿主: 小鼠 Monoclonal KU729 CF®488A
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- 应用备注
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Positive Control: Human cancer K562, HL-60, HEp-2 or HeLa cells.
Known Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Immunocytochemistry (Acetone-fixed cells) (0.5-1.0 μg/mL for 30 minutes at RT)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- XRCC6/XRCC5 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5/6 (XRCC6/XRCC5))
- 别名
- XRCC6 (p70) & XRCC5 (p80) (XRCC6/XRCC5 产品)
- 分子量
- 70kDa & 80kDa
- 基因ID
- 2547, 7520
- UniProt
- P12956, P13010
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