XRCC6/XRCC5 抗体
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- 抗原 See all XRCC6/XRCC5 products
- XRCC6/XRCC5 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5/6 (XRCC6/XRCC5))
- 适用
- 人, 灵长类
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This XRCC6/XRCC5 antibody is un-conjugated
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应用范围
- Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
- 特异性
- Human Ku70+Ku80 / XRCC6+XRCC5
- 无交叉反应
- 小鸡, 小鼠, 大鼠
- 纯化方法
- Protein G purified
- 免疫原
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Nuclear extract of human HL-60 cells.
Type of Immunogen: Cells - 克隆位点
- KU729
- 亚型
- IgG1 kappa
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- 应用备注
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Approved: Flo (0.5 - 1 μg/10 x106), ICC (0.25 - 0.5 μg/mL), IF (0.5 - 1 μg/mL), IHC, IHC-P (0.5 - 1 μg/mL), IP
Usage: This antibody recognizes a dimer of two proteins of 70 kDa (Ku70) and ~80 kDa (Ku80), identified as two subunits of Ku. Antbody KU729 recognizes a conformational epitope of the Ku70 + Ku80 dimer, which is destroyed during Western blotting. The Ku70 + Ku80 dimer is important for function of a 460 kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis. Immunocytochemistry (Acetone-fixed cells) : 0.25-0.5 μg/mL for 30 minutes at RT. - 说明
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Target Species of Antibody: Human
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- Lot specific
- 缓冲液
- PBS, pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 2°C to 8°C.
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- 抗原
- XRCC6/XRCC5 (X-Ray Repair Complementing Defective Repair in Chinese Hamster Cells 5/6 (XRCC6/XRCC5))
- 别名
- Ku70+Ku80 / XRCC6+XRCC5 (XRCC6/XRCC5 产品)
- 背景
- This antibody detects: Ku70+Ku80 / XRCC6+XRCC5
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