C1QB 抗体 (AA 41-188)
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- 抗原 See all C1QB 抗体
- C1QB (Complement Component 1, Q Subcomponent, B Chain (C1QB))
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抗原表位
- AA 41-188
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This C1QB antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
- 特异性
- C1q, a subcomponent of the classical complement pathway, is composed of nine subunits that mediate classical complement activation and thereby play an important role in the immune response. Six of these subunits are disulfide-linked dimers of chains A and B, while three of these subunits, designated C1q-A through C1q-C, are disulfide-linked dimers of chain C. Each chain contains an N-terminal collagen-like region and a C-terminal C1q globular domain. The presence of receptors for C1q on effector cells modulates its activity, which may be antibody-dependent or independent. Macrophages are the primary source of C1q, while anti-inflammatory drugs as well as cytokines differentially regulate expression of the mRNA as well as the protein. C1q deficiency is associated with lupus erythematosus and glomerulonephritis.
- 交叉反应 （详细）
- Human.
- 纯化方法
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- 免疫原
- Recombinant fragment (around aa 41-188) of human C1QB protein (exact sequence is proprietary)
- 克隆位点
- C1QB-2961
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product C1QB Primary Antibody
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anti-Complement Component 1, Q Subcomponent, B Chain (C1QB) (AA 1-253) antibody
C1QB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 1, Q Subcomponent, B Chain (C1QB) (AA 41-188) antibodyC1QB 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal C1QB-2966 unconjugated
anti-Complement Component 1, Q Subcomponent, B Chain (C1QB) (AA 28-253) antibodyC1QB 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 1, Q Subcomponent, B Chain (C1QB) (Internal Region) antibodyC1QB 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 1, Q Subcomponent, B Chain (C1QB) (C-Term) antibodyC1QB 适用: 人, 犬, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 1, Q Subcomponent, B Chain (C1QB) (AA 104-253) antibodyC1QB 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 1, Q Subcomponent, B Chain (C1QB) (AA 1-253) antibodyC1QB 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Complement Component 1, Q Subcomponent, B Chain (C1QB) (C-Term) antibodyC1QB 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 1, Q Subcomponent, B Chain (C1QB) antibodyC1QB 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 1, Q Subcomponent, B Chain (C1QB) (C-Term) antibodyC1QB 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
Positive_Control: Human liver, kidney or brain tissue (IHC).
- 限制
- 仅限研究用
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- 浓度
- 1.0 mg/mL
- 缓冲液
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- 储存液
- Azide free
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- 有效期
- 24 months
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- 抗原
- C1QB (Complement Component 1, Q Subcomponent, B Chain (C1QB))
- 别名
- C1QB (C1QB 产品)
- 别名
- complement C1q B chain antibody, complement component 1, q subcomponent, beta polypeptide antibody, C1QB antibody, C1qb antibody
- 背景
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C1QB, Complement component 1 q subcomponent B chain, Complement component C1q B chain,C1QB / Complement C1q B-Chain
Cellular localisation: Cytoplasmic and Cell Surface - 分子量
- 26-29kDa
- 基因ID
- 713, 8986
- UniProt
- P02746
- 途径
- Complement System
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