C1QB 抗体 (AA 41-188)
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- 抗原 See all C1QB 抗体
- C1QB (Complement Component 1, Q Subcomponent, B Chain (C1QB))
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抗原表位
- AA 41-188
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This C1QB antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Staining Methods (StM)
- 纯化方法
- Purified by Protein A/G
- 免疫原
- Recombinant fragment (around aa 41-188) of human C1QB protein (exact sequence is proprietary)
- 克隆位点
- C1QB-2966
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product C1QB Primary Antibody
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anti-Complement Component 1, Q Subcomponent, B Chain (C1QB) (AA 1-253) antibody
C1QB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 1, Q Subcomponent, B Chain (C1QB) (AA 28-253) antibodyC1QB 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 1, Q Subcomponent, B Chain (C1QB) (Internal Region) antibodyC1QB 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 1, Q Subcomponent, B Chain (C1QB) (C-Term) antibodyC1QB 适用: 人, 犬, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 1, Q Subcomponent, B Chain (C1QB) (AA 104-253) antibodyC1QB 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 1, Q Subcomponent, B Chain (C1QB) (AA 1-253) antibodyC1QB 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Complement Component 1, Q Subcomponent, B Chain (C1QB) (C-Term) antibodyC1QB 适用: 人, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 1, Q Subcomponent, B Chain (C1QB) antibodyC1QB 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 1, Q Subcomponent, B Chain (C1QB) (C-Term) antibodyC1QB 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Complement Component 1, Q Subcomponent, B Chain (C1QB) (AA 107-156) antibodyC1QB 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Positive Control: Human liver, kidney or brain (IHC).
Known Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- C1QB (Complement Component 1, Q Subcomponent, B Chain (C1QB))
- 别名
- C1QB (C1QB 产品)
- 别名
- complement C1q B chain antibody, complement component 1, q subcomponent, beta polypeptide antibody, C1QB antibody, C1qb antibody
- 背景
- C1q, a subcomponent of the classical complement pathway, is composed of nine subunits that mediate classical complement activation and thereby play an important role in the immune response. Six of these subunits are disulfide-linked dimers of chains A and B, while three of these subunits, designated C1q-A through C1q-C, are disulfide-linked dimers of chain C. Each chain contains an N-terminal collagen-like region and a C-terminal C1q globular domain. The presence of receptors for C1q on effector cells modulates its activity, which may be antibody-dependent or independent. Macrophages are the primary source of C1q, while anti-inflammatory drugs as well as cytokines differentially regulate expression of the mRNA as well as the protein. C1q deficiency is associated with lupus erythematosus and glomerulonephritis.
- 分子量
- 26-29kDa
- 基因ID
- 713
- UniProt
- P02746
- 途径
- Complement System
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