Insulin Receptor 抗体 (N-Term)
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- 抗原 See all Insulin Receptor (INSR) 抗体
- Insulin Receptor (INSR)
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Insulin Receptor antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 原理
- Rabbit polyclonal antibody raised against synthetic peptide of INSR.
- 交叉反应
- 人
- 免疫原
- A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human INSR.
- Top Product
- Discover our top product INSR Primary Antibody
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- 应用备注
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-100)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user. - 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- In PBS (0.09 % sodium azide)
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
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Deletion of V335 from the L2 domain of the insulin receptor results in a conformationally abnormal receptor that is unable to bind insulin and causes Donohue's syndrome in a human subject." in: Endocrinology, Vol. 144, Issue 2, pp. 631-7, (2003) (PubMed).
: "Genotype-phenotype correlation in inherited severe insulin resistance." in: Human molecular genetics, Vol. 11, Issue 12, pp. 1465-75, (2002) (PubMed).
: "An arginine to cysteine(252) mutation in insulin receptors from a patient with severe insulin resistance inhibits receptor internalisation but preserves signalling events." in: Diabetologia, Vol. 45, Issue 5, pp. 657-67, (2002) (PubMed).
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Deletion of V335 from the L2 domain of the insulin receptor results in a conformationally abnormal receptor that is unable to bind insulin and causes Donohue's syndrome in a human subject." in: Endocrinology, Vol. 144, Issue 2, pp. 631-7, (2003) (PubMed).
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- 抗原
- Insulin Receptor (INSR)
- 别名
- CD220 / INSR (INSR 产品)
- 别名
- CD220 antibody, HHF5 antibody, 4932439J01Rik antibody, D630014A15Rik antibody, IR antibody, IR-A antibody, IR-B antibody, 18402 antibody, CG18402 antibody, DIHR antibody, DILR antibody, DIR antibody, DIRH antibody, DIRbeta antibody, DInR antibody, DInr antibody, Dir-a antibody, Dir-b antibody, Dmel\\CG18402 antibody, INR antibody, INS antibody, Inr antibody, Inr-alpha antibody, Inr-beta antibody, InsR antibody, dINR antibody, dIR antibody, dIRH antibody, dInR antibody, dInr antibody, dInsR antibody, dinr antibody, dir antibody, er10 antibody, inr antibody, insulin/insulin-like growth factor receptor antibody, l(3)05545 antibody, l(3)93Dj antibody, l(3)er10 antibody, lnR antibody, ir-A antibody, CTK-1 antibody, ir antibody, INSR antibody, NV14476 antibody, cd220 antibody, hhf5 antibody, insulin receptor antibody, Insulin-like receptor antibody, insulin receptor L homeolog antibody, INSR antibody, Insr antibody, InR antibody, LOC100122567 antibody, LOC100451802 antibody, insr.L antibody
- 基因ID
- 3643
- 途径
- NF-kappaB Signaling, RTK signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
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