WNT5A 抗体 (AA 301-381)
(3 references)-
- 抗原 See all WNT5A 抗体
- WNT5A (Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A))
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抗原表位
- AA 301-381
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适用
- 人, 小鼠, 大鼠, 犬
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This WNT5A antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 犬, 人, 小鼠, 大鼠
- 预测反应
- Cow,Pig,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human WNT5A
- 亚型
- IgG
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anti-Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A) (AA 185-213) antibody
WNT5A 适用: 人, 小鼠, 大鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22340 unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A) (AA 62-380) antibodyWNT5A 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A) (AA 180-229) antibodyWNT5A 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, Bat, Pig WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A) antibodyWNT5A 适用: 人 WB, IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 6F2 unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A) (Middle Region) antibodyWNT5A 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 兔, 马, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A) (AA 185-213) antibodyWNT5A 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A) (AA 62-380) antibodyWNT5A 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A) (AA 62-380) antibodyWNT5A 适用: 小鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C3 unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A) (AA 201-300) antibodyWNT5A 适用: 人 ELISA, IHC (p) 宿主: 小鼠 Monoclonal 3A4 unconjugated
anti-Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A) (AA 190-230) antibodyWNT5A 适用: 人, 小鼠, 大鼠, Cow, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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: "Snail1 is positively correlated with atrial fibrosis in patients with atrial fibrillation and rheumatic heart disease." in: Experimental and therapeutic medicine, Vol. 14, Issue 5, pp. 4231-4237, (2017) (PubMed).
: "Macrophage-derived extracellular vesicle-packaged WNTs rescue intestinal stem cells and enhance survival after radiation injury." in: Nature communications, Vol. 7, pp. 13096, (2016) (PubMed).
: "Macrophages mediate a switch between canonical and non-canonical Wnt pathways in canine mammary tumors." in: PLoS ONE, Vol. 9, Issue 1, pp. e83995, (2014) (PubMed).
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: "Snail1 is positively correlated with atrial fibrosis in patients with atrial fibrillation and rheumatic heart disease." in: Experimental and therapeutic medicine, Vol. 14, Issue 5, pp. 4231-4237, (2017) (PubMed).
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- 抗原
- WNT5A (Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A))
- 别名
- WNT5A (WNT5A 产品)
- 别名
- hWNT5A antibody, wnt-5A antibody, wnt5a-B antibody, WNT5A antibody, 8030457G12Rik antibody, Wnt-5a antibody, Wnt family member 5A antibody, Wnt family member 5A S homeolog antibody, wingless-type MMTV integration site family, member 5a antibody, wingless-type MMTV integration site family, member 5A antibody, wingless-related MMTV integration site 5A antibody, Wnt signaling ligand antibody, WNT5A antibody, Wnt5a antibody, wnt5a.S antibody, wnt5a antibody, LOC578814 antibody, wnt5 antibody
- 背景
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Synonyms: hWNT5A, Protein Wnt-5a, WNT5A
Background: Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression. Suppression of the canonical pathway allows chondrogenesis to occur and inhibits tumor formation. Stimulates cell migration. Decreases proliferation, migration, invasiveness and clonogenicity of carcinoma cells and may act as a tumor suppressor. Mediates motility of melanoma cells. Required during embryogenesis for extension of the primary anterior-posterior axis and for outgrowth of limbs and the genital tubercle. Inhibits type II collagen expression in chondrocytes.
- 基因ID
- 7474
- UniProt
- P41221
- 途径
- WNT signaling, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Cell Size, Tube Formation
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