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WNT5A 抗体 (AA 62-380)

WNT5A 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7166304
发货至: 中国
  • 抗原 See all WNT5A 抗体
    WNT5A (Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A))
    抗原表位
    • 16
    • 10
    • 8
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    • 7
    • 6
    • 6
    • 4
    • 3
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    • 1
    • 1
    • 1
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    AA 62-380
    适用
    • 80
    • 36
    • 25
    • 18
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 82
    • 8
    • 2
    克隆类型
    • 70
    • 22
    多克隆
    标记
    • 42
    • 9
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This WNT5A antibody is un-conjugated
    应用范围
    • 79
    • 43
    • 29
    • 28
    • 14
    • 14
    • 13
    • 7
    • 6
    • 5
    • 5
    • 3
    • 1
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    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)
    交叉反应
    人, 小鼠
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Protein Wnt-5a protein (62-380AA)
    亚型
    IgG
    Top Product
    Discover our top product WNT5A Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    WNT5A (Wingless-Type MMTV Integration Site Family, Member 5A (WNT5A))
    别名
    WNT5A (WNT5A 产品)
    别名
    hWNT5A antibody, wnt-5A antibody, wnt5a-B antibody, WNT5A antibody, 8030457G12Rik antibody, Wnt-5a antibody, Wnt family member 5A antibody, Wnt family member 5A S homeolog antibody, wingless-type MMTV integration site family, member 5a antibody, wingless-type MMTV integration site family, member 5A antibody, wingless-related MMTV integration site 5A antibody, Wnt signaling ligand antibody, WNT5A antibody, Wnt5a antibody, wnt5a.S antibody, wnt5a antibody, LOC578814 antibody, wnt5 antibody
    背景

    Background: Ligand for members of the frizzled family of seven transmembrane receptors. Can activate or inhibit canonical Wnt signaling, depending on receptor context. In the presence of FZD4, activates beta-catenin signaling. In the presence of ROR2, inhibits the canonical Wnt pathway by promoting beta-catenin degradation through a GSK3-independent pathway which involves down-regulation of beta-catenin-induced reporter gene expression. Suppression of the canonical pathway allows chondrogenesis to occur and inhibits tumor formation. Stimulates cell migration. Decreases proliferation, migration, invasiveness and clonogenicity of carcinoma cells and may act as a tumor suppressor. Mediates motility of melanoma cells. Required during embryogenesis for extension of the primary anterior-posterior axis and for outgrowth of limbs and the genital tubercle. Inhibits type II collagen expression in chondrocytes.

    Aliases: hWNT 5A antibody, hWNT5A antibody, Protein Wnt 5a antibody, Protein Wnt-5a antibody, Protein Wnt5a antibody, Wingless type MMTV integration site family member 5A antibody, Wnt 5a antibody, WNT 5A protein antibody, WNT 5A protein precursor antibody, WNT5A antibody, WNT5A protein precursor antibody, WNT5A_HUMAN antibody

    UniProt
    P41221
    途径
    WNT signaling, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Regulation of Cell Size, Tube Formation
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