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- 抗原 See all Nav1.8 (SCN10A) 抗体
- Nav1.8 (SCN10A) (Sodium Channel, Voltage-Gated, Type X, alpha Subunit (SCN10A))
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抗原表位
- C-Term
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适用
- 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Nav1.8 antibody is un-conjugated
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应用范围
- Immunohistochemistry (IHC), Western Blotting (WB), Fluorescence Microscopy (FM)
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Anti-NAV1.8 Antibody was purified by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with NAV1.8 from human, mouse, and rat based on 100% homology with the immunizing sequence. No cross reactivity against other Nav channels. Cross-reactivity with NAV1.8 from other sources has not been determined. Ion Channels research.
- 免疫原
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Immunogen: Nav1.8 Antibody was produced in mice by repeated immunizations raised against a fusion protein corresponding near the cytoplasmic C-terminus region of rat Nav1.8.
Immunogen Type: Recombinant Protein
- 克隆位点
- S134-12
- 亚型
- IgG2a
- Top Product
- Discover our top product SCN10A Primary Antibody
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anti-Sodium Channel, Voltage-Gated, Type X, alpha Subunit (SCN10A) (AA 1724-1956) antibody
SCN10A 适用: 大鼠 IHC, WB, IF, ICC, AA 宿主: 小鼠 Monoclonal S134 unconjugated
anti-Sodium Channel, Voltage-Gated, Type X, alpha Subunit (SCN10A) (AA 1724-1956) antibody (HRP)SCN10A 适用: 大鼠 IHC, WB, IF, ICC, AA 宿主: 小鼠 Monoclonal S134 HRP
anti-Sodium Channel, Voltage-Gated, Type X, alpha Subunit (SCN10A) (AA 1724-1956) antibody (FITC)SCN10A 适用: 大鼠 IHC, WB, IF, ICC, AA 宿主: 小鼠 Monoclonal S134 FITC
anti-Sodium Channel, Voltage-Gated, Type X, alpha Subunit (SCN10A) (AA 1724-1956) antibody (Biotin)SCN10A 适用: 大鼠 IHC, WB, IF, ICC, AA 宿主: 小鼠 Monoclonal S134 Biotin
anti-Sodium Channel, Voltage-Gated, Type X, alpha Subunit (SCN10A) (AA 1724-1956) antibody (PE)SCN10A 适用: 大鼠 IHC, WB, IF, ICC, AA 宿主: 小鼠 Monoclonal S134 PE
anti-Sodium Channel, Voltage-Gated, Type X, alpha Subunit (SCN10A) (AA 1724-1956) antibody (APC)SCN10A 适用: 大鼠 IHC, WB, IF, ICC, AA 宿主: 小鼠 Monoclonal S134 APC
anti-Sodium Channel, Voltage-Gated, Type X, alpha Subunit (SCN10A) (AA 1724-1956) antibody (PerCP)SCN10A 适用: 大鼠 IHC, WB, IF, ICC, AA 宿主: 小鼠 Monoclonal S134 PerCP
anti-Sodium Channel, Voltage-Gated, Type X, alpha Subunit (SCN10A) (AA 1724-1956) antibody (Atto 594)SCN10A 适用: 大鼠 IHC, WB, IF, ICC, AA 宿主: 小鼠 Monoclonal S134 Atto 594
anti-Sodium Channel, Voltage-Gated, Type X, alpha Subunit (SCN10A) (AA 1724-1956) antibody (Atto 488)SCN10A 适用: 大鼠 IHC, WB, IF, ICC, AA 宿主: 小鼠 Monoclonal S134 Atto 488
anti-Sodium Channel, Voltage-Gated, Type X, alpha Subunit (SCN10A) (AA 1724-1956) antibody (Atto 390)SCN10A 适用: 大鼠 IHC, WB, IF, ICC, AA 宿主: 小鼠 Monoclonal S134 Atto 390
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- 应用备注
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Immunohistochemistry Dilution: 0.1-1.0 μg/mL
Application Note: Anti-NAV1.8 Antibody is suitable for use in WB, IHC and IF microscopy. Expect a band approximately ~220 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.
Western Blot Dilution: 1-10 μg/mL
IF Microscopy Dilution: 1.0-10 μg/mL
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Stabilizer: 50 % (v/v) Glycerol
0.09 % (w/v) Sodium Azide - 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- RT,4 °C,-20 °C
- 储存方法
- Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
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- 抗原
- Nav1.8 (SCN10A) (Sodium Channel, Voltage-Gated, Type X, alpha Subunit (SCN10A))
- 别名
- NAV1.8 (SCN10A 产品)
- 别名
- Nav1.8 antibody, PN3 antibody, SNS antibody, hPN3 antibody, Na(V)1.8 antibody, sodium channel, voltage-gated, type X, alpha antibody, sodium voltage-gated channel alpha subunit 10 antibody, Scn10a antibody, SCN10A antibody
- 背景
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Synonyms: PN3, Na(V)1.8, Scn10a, Sodium channel protein type 10 subunit alpha, Peripheral nerve sodium channel 3, Sensory neuron sodium channel, Sodium channel protein type X subunit alpha, Voltage-gated sodium channel subunit alpha Nav1.8
Background: Nav1.8 is a voltage-gated sodium channel and plays a critical role in the generation and conduction of action potentials and is thus important for electrical signaling by most excitable cells. Therapeutically, the association of pain insensitivity with the loss of function of a certain sodium channel may have implications. Since Nav1.8 is not present in cardiac muscle or neurons in the central nervous system, blockers of Nav1.8 will not have direct action on these cells and thus can have less side effects than current pain medications. By performing more studies, there is a possibility to develop a new generation of drugs that can reduce the pain intensity in animals.
Gene Name: Scn10a
- 基因ID
- 29571
- NCBI登录号
- NP_058943
- UniProt
- Q62968
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