Nav1.8 抗体 (AA 1724-1956) (Biotin)
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Quick Overview for Nav1.8 抗体 (AA 1724-1956) (Biotin) (ABIN2483063)
抗原
See all Nav1.8 (SCN10A) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1724-1956
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特异性
- Detects ~220 kDa. No cross reactivity against other Nav channels.
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交叉反应
- 人, 猴, 小鼠, 大鼠
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纯化方法
- Protein G Purified
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免疫原
- Fusion protein amino acids 1724-1956 of rat Nav1.8
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亚型
- IgG2a
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anti-Sodium Channel, Voltage-Gated, Type X, alpha Subunit (SCN10A) (AA 1724-1956) antibody (FITC)
SCN10A 适用: 大鼠 IHC, WB, IF, ICC, AA 宿主: 小鼠 Monoclonal S134 FITC
anti-Sodium Channel, Voltage-Gated, Type X, alpha Subunit (SCN10A) (AA 1724-1956) antibody (PerCP)SCN10A 适用: 大鼠 IHC, WB, IF, ICC, AA 宿主: 小鼠 Monoclonal S134 PerCP
anti-Sodium Channel, Voltage-Gated, Type X, alpha Subunit (SCN10A) (AA 1724-1956) antibody (PE)SCN10A 适用: 大鼠 IHC, WB, IF, ICC, AA 宿主: 小鼠 Monoclonal S134 PE
anti-Sodium Channel, Voltage-Gated, Type X, alpha Subunit (SCN10A) (AA 1724-1956) antibody (Atto 390)SCN10A 适用: 大鼠 IHC, WB, IF, ICC, AA 宿主: 小鼠 Monoclonal S134 Atto 390
anti-Sodium Channel, Voltage-Gated, Type X, alpha Subunit (SCN10A) (AA 1724-1956) antibody (Atto 488)SCN10A 适用: 大鼠 IHC, WB, IF, ICC, AA 宿主: 小鼠 Monoclonal S134 Atto 488
anti-Sodium Channel, Voltage-Gated, Type X, alpha Subunit (SCN10A) (AA 1724-1956) antibody (Atto 594)SCN10A 适用: 大鼠 IHC, WB, IF, ICC, AA 宿主: 小鼠 Monoclonal S134 Atto 594
anti-Sodium Channel, Voltage-Gated, Type X, alpha Subunit (SCN10A) (AA 1724-1956) antibody (HRP)SCN10A 适用: 大鼠 IHC, WB, IF, ICC, AA 宿主: 小鼠 Monoclonal S134 HRP
anti-Sodium Channel, Voltage-Gated, Type X, alpha Subunit (SCN10A) (AA 1724-1956) antibody (APC)SCN10A 适用: 大鼠 IHC, WB, IF, ICC, AA 宿主: 小鼠 Monoclonal S134 APC
anti-Sodium Channel, Voltage-Gated, Type X, alpha Subunit (SCN10A) (AA 1724-1956) antibodySCN10A 适用: 大鼠 IHC, WB, IF, ICC, AA 宿主: 小鼠 Monoclonal S134 unconjugated
anti-Sodium Channel, Voltage-Gated, Type X, alpha Subunit (SCN10A) antibodySCN10A 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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- WB (1:1000)
- IHC (1:1000)
- ICC/IF (1:100)
- optimal dilutions for assays should be determined by the user.
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说明
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1 μg/ml of ABIN2483063 was sufficient for detection of Nav1.8 in 10 μg of COS cell lysate transiently expressing Nav1.8 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Conjugated antibodies should be stored at 4°C
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- Nav1.8 (SCN10A) (Sodium Channel, Voltage-Gated, Type X, alpha Subunit (SCN10A))
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别名
- Nav1.8
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背景
- Nav1.8 is a voltage-gated sodium channel and plays a critical role in the generation and conduction of action potentials and is thus important for electrical signaling by most excitable cells. Therapeutically, the association of pain insensitivity with the loss of function of a certain sodium channel may have implications. Since Nav1.8 is not present in cardiac muscle or neurons in the central nervous system, blockers of Nav1.8 will not have direct action on these cells and thus can have less side effects than current pain medications. By performing more studies, there is a possibility to develop a new generation of drugs that can reduce the pain intensity in animals.
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基因ID
- 29571
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NCBI登录号
- NP_058943
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UniProt
- Q62968
抗原
-
