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Nav1.8 抗体 (AA 1724-1956) (FITC)

SCN10A 适用: 大鼠 IHC, WB, IF, ICC, AA 宿主: 小鼠 Monoclonal S134 FITC
产品编号 ABIN2483064
发货至: 中国
  • 抗原 See all Nav1.8 (SCN10A) 抗体
    Nav1.8 (SCN10A) (Sodium Channel, Voltage-Gated, Type X, alpha Subunit (SCN10A))
    抗原表位
    • 12
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 1724-1956
    适用
    • 18
    • 16
    • 3
    • 1
    大鼠
    宿主
    • 17
    • 14
    • 1
    • 1
    小鼠
    克隆类型
    • 19
    • 14
    单克隆
    标记
    • 13
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Nav1.8 antibody is conjugated to FITC
    应用范围
    • 19
    • 19
    • 15
    • 12
    • 10
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (IHC), Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Antibody Array (AA)
    特异性
    Detects ~220 kDa. No cross reactivity against other Nav channels.
    交叉反应
    人, 猴, 小鼠, 大鼠
    纯化方法
    Protein G Purified
    免疫原
    Fusion protein amino acids 1724-1956 of rat Nav1.8
    克隆位点
    S134
    亚型
    IgG2a
    Top Product
    Discover our top product SCN10A Primary Antibody
  • 应用备注
    • WB (1:1000)
    • IHC (1:1000)
    • ICC/IF (1:100)
    • optimal dilutions for assays should be determined by the user.
    说明

    1 μg/ml of ABIN2483064 was sufficient for detection of Nav1.8 in 10 μg of COS cell lysate transiently expressing Nav1.8 by colorimetric immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Conjugated antibodies should be stored at 4°C
  • 抗原
    Nav1.8 (SCN10A) (Sodium Channel, Voltage-Gated, Type X, alpha Subunit (SCN10A))
    别名
    Nav1.8 (SCN10A 产品)
    别名
    Nav1.8 antibody, PN3 antibody, SNS antibody, hPN3 antibody, Na(V)1.8 antibody, sodium channel, voltage-gated, type X, alpha antibody, sodium voltage-gated channel alpha subunit 10 antibody, Scn10a antibody, SCN10A antibody
    背景
    Nav1.8 is a voltage-gated sodium channel and plays a critical role in the generation and conduction of action potentials and is thus important for electrical signaling by most excitable cells. Therapeutically, the association of pain insensitivity with the loss of function of a certain sodium channel may have implications. Since Nav1.8 is not present in cardiac muscle or neurons in the central nervous system, blockers of Nav1.8 will not have direct action on these cells and thus can have less side effects than current pain medications. By performing more studies, there is a possibility to develop a new generation of drugs that can reduce the pain intensity in animals.
    基因ID
    29571
    NCBI登录号
    NP_058943
    UniProt
    Q62968
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