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EPAS1 抗体 (Internal Region)

Name: EPAS1 抗体 (Internal Region)
SKU: ABIN6655142
Availability: OutOfStock

EPAS1 适用: 人 WB, ELISA, IHC, IP 宿主: 小鼠 Monoclonal EP190B unconjugated

HIF2 alpha Western Blot. (EPAS1 抗体 (Internal Region))

HIF2 alpha Immunohistochemistry. (EPAS1 抗体 (Internal Region))

IHC

2 images

产品编号 ABIN6655142

发货至: 中国

Datasheet as PDF

抗原 See all EPAS1 抗体

EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))
抗原表位
16

11

9

7

7

6

6

6

6

3

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Internal Region
适用
90

49

43

18

17

3

3

2

2

2

2

2

1

1

1

1

1

1

1
人
宿主
100

9

1

1
小鼠
Compatible Secondaries
克隆类型
93

18
单克隆
标记
55

14

7

5

5

4

2

2

2

2

2

2

2

2

1

1

1

1

1
This EPAS1 antibody is un-conjugated
应用范围
90

45

30

23

14

13

13

13

13

11

5

4

4

2

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunoprecipitation (IP)

纯化方法

Anti-HIF2α Antibody was purified by Protein G chromatography. This monoclonal antibody is specific for human HIF2α protein. A BLAST analysis was used to suggest cross-reactivity with HIF2α from human based on 100% homology with the immunizing sequence. Cross-reactivity with HIF2α from other sources has not been determined. Oxidative Stress/Cell Signaling research.

免疫原

Immunogen: HIF2 alpha Antibody was produced in mice by repeated immunizations raised against a recombinant protein corresponding to an internal region of human EPAS-1 (HIF2alpha).
Immunogen Type: Recombinant Protein

克隆位点

EP190B

亚型

IgG1

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anti-Endothelial PAS Domain Protein 1 (EPAS1) antibody
EPAS1 适用: 人 WB, ChIP 宿主: 兔 Polyclonal unconjugated

anti-Endothelial PAS Domain Protein 1 (EPAS1) (AA 535-631) antibody
EPAS1 适用: 人, 小鼠, 大鼠, Hamster WB, ELISA, IHC, IP, FACS, ICC, IF, ChIP 宿主: 小鼠 Monoclonal ep190b unconjugated

anti-Endothelial PAS Domain Protein 1 (EPAS1) (AA 1-130) antibody
EPAS1 适用: 人, 小鼠, 大鼠, 猴, 绵羊 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

应用备注

Immunohistochemistry Dilution: User Optimized
Application Note: Anti-HIF2α Antibody is recommended for use in ELISA, WB, IHC and IF microscopy. Antibody is provided in PBS pH 7.4. Specific conditions for reactivity should be optimized by the end user.
Immunoprecipitation Dilution: User Optimized
ELISA Dilution: 1:200
Western Blot Dilution: 1:100 - 1:500

限制

仅限研究用
状态

Liquid

缓冲液

Buffer:
Stabilizer: 50 % (v/v) Glycerol
0.09 % (w/v) Sodium Azide

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

RT,4 °C,-20 °C

储存方法

Store vial at -20° C prior to opening. Aliquot contents and freeze at -20° C or below for extended storage. Avoid cycles of freezing and thawing. Centrifuge product if not completely clear after standing at room temperature. This product is stable for several weeks at 4° C as an undiluted liquid. Dilute only prior to immediate use.
抗原

EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))

别名

HIF2 alpha (EPAS1 产品)

别名

EPAS1 antibody, ECYT4 antibody, HIF2A antibody, HLF antibody, MOP2 antibody, PASD2 antibody, bHLHe73 antibody, HIF-2alpha antibody, HRF antibody, Hif2a antibody, bhlhe73 antibody, ecyt4 antibody, hif2 antibody, hif2a antibody, hif2alpha antibody, hlf antibody, mop2 antibody, pasd2 antibody, EPAS antibody, EPAS-1 antibody, endothelial PAS domain protein 1 antibody, endothelial PAS domain protein 1 L homeolog antibody, EPAS1 antibody, epas1 antibody, Epas1 antibody, epas1.L antibody

背景

Synonyms: mouse anti-HIF2 alpha Antibody, mouse anti-HIF2a Antibody, ECYT4, EPAS1, HIF2alpha, HIF1 Alpha like factor, HLF, Hypoxia inducible factor 2 alpha, MOP2, PASD2, Endothelial PAS domain-containing protein 1, Basic-helix-loop-helix-PAS protein MOP2, Class E basic helix-loop-helix protein 73
Background: Members of the hypoxia-inducible factor (HIF) family of transcription factors regulate the cellular response to hypoxia. HIF2-Alpha is involved in catecholamine homeostasis, vascular remodeling, physiological angiogenesis and adipogenesis. It is overexpressed in many cancerous tissues, but its exact role in tumour progression remains to be clarified. Studies suggest that in the case of non-small cell lung cancer, HIF2-Alpha actually is a promoter of tumor growth and progression in a solid tumor. Other data suggests that HIF2-Alpha is an important regulator of innate immunity, and therefore may be useful in the therapeutic target for treating inflammatory disorders and cancer.
Gene Name: EPAS1

基因ID

2034

NCBI登录号

NP_001421

UniProt

Q99814

途径

Signaling Events mediated by VEGFR1 and VEGFR2, Warburg Effect