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EPAS1 抗体

EPAS1 适用: 人 WB, ChIP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855683
发货至: 中国
  • 抗原 See all EPAS1 抗体
    EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))
    适用
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    宿主
    • 100
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    克隆类型
    • 92
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    多克隆
    标记
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    This EPAS1 antibody is un-conjugated
    应用范围
    • 92
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    Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
    交叉反应
    人, 斑马鱼
    产品特性
    Rabbit Polyclonal antibody to HIF2 alpha (endothelial PAS domain protein 1)
    HIF2 alpha antibody [N1N3]
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human HIF2 alpha. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product EPAS1 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: HepG2 (1% O2 treatment for 24hr)

    Validation: Orthogonal

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Ko, Tsai, Tseng, Cheng, Huang, Wu, Chung, Hsieh, Sun, Hwang, Yuh, Huang, Pai, Tzou, Hu: "Integration of CNS survival and differentiation by HIF2α." in: Cell death and differentiation, Vol. 18, Issue 11, pp. 1757-70, (2012) (PubMed).

  • 抗原
    EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))
    别名
    endothelial PAS domain protein 1 (EPAS1 产品)
    别名
    EPAS1 antibody, ECYT4 antibody, HIF2A antibody, HLF antibody, MOP2 antibody, PASD2 antibody, bHLHe73 antibody, HIF-2alpha antibody, HRF antibody, Hif2a antibody, bhlhe73 antibody, ecyt4 antibody, hif2 antibody, hif2a antibody, hif2alpha antibody, hlf antibody, mop2 antibody, pasd2 antibody, EPAS antibody, EPAS-1 antibody, endothelial PAS domain protein 1 antibody, endothelial PAS domain protein 1 L homeolog antibody, EPAS1 antibody, epas1 antibody, Epas1 antibody, epas1.L antibody
    背景
    This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4.

    Cellular Localization: Nucleus
    分子量
    96 kDa
    基因ID
    2034
    UniProt
    Q99814
    途径
    Signaling Events mediated by VEGFR1 and VEGFR2, Warburg Effect
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