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HLA-A 抗体 (AA 70-99)

HLA-A 适用: 小鼠 WB 宿主: 小鼠 Monoclonal 7G7F9 unconjugated
产品编号 ABIN659014
发货至: 中国
  • 抗原 See all HLA-A 抗体
    HLA-A (Major Histocompatibility Complex, Class I, A (HLA-A))
    抗原表位
    • 9
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 70-99
    适用
    • 57
    • 14
    • 6
    • 3
    • 1
    小鼠
    宿主
    • 34
    • 29
    • 3
    小鼠
    克隆类型
    • 33
    • 33
    单克隆
    标记
    • 33
    • 7
    • 7
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This HLA-A antibody is un-conjugated
    应用范围
    • 38
    • 30
    • 26
    • 19
    • 18
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    预测反应
    H
    纯化方法
    This antibody is purified through a protein G column, followed by dialysis against PBS.
    免疫原
    This HLA-A antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 70-99 amino acids from the Central region of human HLA-A.
    克隆位点
    7G7F9
    亚型
    Ig Fraction, IgG1
    Top Product
    Discover our top product HLA-A Primary Antibody
  • 应用备注
    WB: 1:100~250
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    HLA-A Antibody(Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
    有效期
    6 months
  • 抗原
    HLA-A (Major Histocompatibility Complex, Class I, A (HLA-A))
    别名
    HLA-A (HLA-A 产品)
    别名
    HLAA antibody, major histocompatibility complex, class I, A antibody, HLA-A antibody
    背景
    HLA-A belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-A alleles have been described.
    分子量
    40841
    基因ID
    3105
    NCBI登录号
    NP_002107
    UniProt
    P04439
    途径
    TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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