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- 抗原 See all HLA-A 抗体
- HLA-A (Major Histocompatibility Complex, Class I, A (HLA-A))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This HLA-A antibody is un-conjugated
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应用范围
- Flow Cytometry (FACS), Immunofluorescence (IF)
- 特异性
- HLA-A, with HLA-B and HLA-C, belongs to major histocompatibility complex (MHC) class I antigens and expresses constitutively on all nucleated cells. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation. This MAb is useful for HLA molecular typing of peripheral blood leukocytes as well as a large number of leukemic cell lines. It reacts with an intralocus determinant present on a limited number of HLA-A locus-encoded gene products (HLA-A2, -A3, -A28, -A29, -A30, -A31 and -Aw33). Its epitope maps between aa65-to-aa80 of the 1 domain of the HLA-A. This MAb recognizes an intralocus determinant present on a limited number of HLA-A locus-encoded gene products (HLA-A2, -A3, A28, -A29, -A30, -A31 and -Aw33). Furthermore, by testing its reactivity with HLA-A2 natural variants and mutants, the importance of amino acid residues 79 and/or 80 of the alpha1 domain was demonstrated in the formation of an intralocus HLA-A determinant.
- 免疫原
- Normal human peripheral blood lymphocytes
- 克隆位点
- 108-2C5
- 亚型
- IgG1 kappa
- Top Product
- Discover our top product HLA-A Primary Antibody
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anti-Major Histocompatibility Complex, Class I, A (HLA-A) (AA 35-285) antibody
HLA-A 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I, A (HLA-A) antibodyHLA-A 适用: 人, 小鼠, 大鼠 WB, IF, IHC 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I, A (HLA-A) (AA 1-365) antibodyHLA-A 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I, A (HLA-A) (AA 1-365) antibodyHLA-A 适用: 人 FACS, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I, A (HLA-A) (AA 24-365) antibodyHLA-A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2D6 unconjugated
anti-Major Histocompatibility Complex, Class I, A (HLA-A) antibodyHLA-A 适用: 人 WB, IHC, IP 宿主: 兔 Monoclonal unconjugated
anti-Major Histocompatibility Complex, Class I, A (HLA-A) antibodyHLA-A 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I, A (HLA-A) (AA 70-99) antibodyHLA-A 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal unconjugated
anti-Major Histocompatibility Complex, Class I, A (HLA-A) (AA 82-106), (N-Term) antibodyHLA-A 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I, A (HLA-A) antibodyHLA-A 适用: 人, 小鼠, 大鼠 WB, IF, IHC, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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Positive Control: Raji, THP-1 and Jurkat cells. Tonsil or lymph node.
Known Application: Flow Cytometry (1-2 μg/million cells), ,Immunofluorescence (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-80 °C
- 储存方法
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- 有效期
- 24 months
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- 抗原
- HLA-A (Major Histocompatibility Complex, Class I, A (HLA-A))
- 别名
- HLA-A (HLA-A 产品)
- 别名
- HLAA antibody, major histocompatibility complex, class I, A antibody, HLA-A antibody
- 分子量
- ~41kDa
- 基因ID
- 3105
- UniProt
- P01889, P30443, P30499
- 途径
- TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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