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NSD1 抗体

NSD1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6572111
发货至: 中国
  • 抗原 See all NSD1 抗体
    NSD1 (Nuclear Receptor Binding SET Domain Protein 1 (NSD1))
    适用
    • 26
    • 16
    • 15
    • 1
    人, 小鼠
    宿主
    • 19
    • 8
    克隆类型
    • 20
    • 7
    多克隆
    标记
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NSD1 antibody is un-conjugated
    应用范围
    • 13
    • 13
    • 9
    • 8
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of human NSD1
    亚型
    IgG
    Top Product
    Discover our top product NSD1 Primary Antibody
  • 应用备注
    WB 1:500 - 1:1000
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    Buffer: PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    NSD1 (Nuclear Receptor Binding SET Domain Protein 1 (NSD1))
    别名
    NSD1 (NSD1 产品)
    别名
    NSD1 antibody, sto antibody, kmt3b antibody, sotos antibody, ara267 antibody, ARA267 antibody, KMT3B antibody, SOTOS antibody, SOTOS1 antibody, STO antibody, AI528500 antibody, nuclear receptor binding SET domain protein 1 antibody, histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific antibody, nuclear receptor-binding SET-domain protein 1 antibody, NSD1 antibody, nsd1 antibody, Nsd1 antibody, LOC540197 antibody
    背景

    Synonyms: Nuclear Receptor Binding SET Domain Protein 1,Nuclear Receptor-Binding SET Domain-Containing Protein 1,Androgen Receptor-Associated Protein Of 267 KDa,Androgen Receptor Coactivator 267 KDa Protein,NR-Binding SET Domain-Containing Protein,Lysine N-Methyltransferase 3B,H3-K36-HMTase,H4-K20-HMTase,EC 2.1.1.43.

    Background: This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98-kd on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene.

    分子量

    Observed_MW: 297kDa

    Calculated_MW: 267kDa/284kDa/296kDa

    基因ID
    64324
    UniProt
    Q96L73
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