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NSD1 抗体 (AA 2401-2600) (HRP)

NSD1 适用: 人, 小鼠, 大鼠 ELISA, IHC (fro), IHC (p) 宿主: 兔 Polyclonal HRP
产品编号 ABIN904247
发货至: 中国
  • 抗原 See all NSD1 抗体
    NSD1 (Nuclear Receptor Binding SET Domain Protein 1 (NSD1))
    抗原表位
    • 14
    • 3
    • 2
    • 2
    AA 2401-2600
    适用
    • 26
    • 16
    • 14
    • 1
    人, 小鼠, 大鼠
    宿主
    • 19
    • 8
    克隆类型
    • 20
    • 7
    多克隆
    标记
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NSD1 antibody is conjugated to HRP
    应用范围
    • 13
    • 13
    • 9
    • 8
    • 4
    • 3
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Dog,Cow,Sheep,Pig,Horse,Rabbit
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human NSD1
    亚型
    IgG
    Top Product
    Discover our top product NSD1 Primary Antibody
  • 应用备注
    IHC-P 1:200-400
    IHC-F 1:100-500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    注意事项
    Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    NSD1 (Nuclear Receptor Binding SET Domain Protein 1 (NSD1))
    别名
    NSD1 (NSD1 产品)
    别名
    NSD1 antibody, sto antibody, kmt3b antibody, sotos antibody, ara267 antibody, ARA267 antibody, KMT3B antibody, SOTOS antibody, SOTOS1 antibody, STO antibody, AI528500 antibody, nuclear receptor binding SET domain protein 1 antibody, histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific antibody, nuclear receptor-binding SET-domain protein 1 antibody, NSD1 antibody, nsd1 antibody, Nsd1 antibody, LOC540197 antibody
    背景

    Synonyms: Androgen receptor coactivator 267 kDa protein, Androgen receptor-associated protein of 267 kDa, ARA267, H3 K36 HMTase, H3-K36-HMTase, H4 K20 HMTase, H4-K20-HMTase, Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specic, KMT3B, Lysine N-methyltransferase 3B, NR binding SET domain containing protein, NR-binding SET domain-containing protein, Nsd1, NSD1_HUMAN, Nuclear receptor binding SET domain containing protein 1, Nuclear receptor-binding SET domain-containing protein 1.

    Background: This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98-kd on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].

    基因ID
    64324
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