NSD1 抗体
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- 抗原 See all NSD1 抗体
- NSD1 (Nuclear Receptor Binding SET Domain Protein 1 (NSD1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NSD1 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人, 小鼠
- 纯化方法
- Antigen affinity purification
- 免疫原
- Synthetic peptide of Human NSD1
- 亚型
- IgG
- Top Product
- Discover our top product NSD1 Primary Antibody
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- 应用备注
- ELISA:1:2000-1:5000, IHC:1:25-1:100,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- -20 °C, pH 7.4 PBS, 0.05 % Sodium azide, 40 % Glycerol
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- NSD1 (Nuclear Receptor Binding SET Domain Protein 1 (NSD1))
- 别名
- NSD1 (NSD1 产品)
- 别名
- NSD1 antibody, sto antibody, kmt3b antibody, sotos antibody, ara267 antibody, ARA267 antibody, KMT3B antibody, SOTOS antibody, SOTOS1 antibody, STO antibody, AI528500 antibody, nuclear receptor binding SET domain protein 1 antibody, histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific antibody, nuclear receptor-binding SET-domain protein 1 antibody, NSD1 antibody, nsd1 antibody, Nsd1 antibody, LOC540197 antibody
- 背景
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Background: This gene encodes a protein containing a SET domain, 2 LXXLL motifs, 3 nuclear translocation signals (NLSs), 4 plant homeodomain (PHD) finger regions, and a proline-rich region. The encoded protein enhances androgen receptor (AR) transactivation, and this enhancement can be increased further in the presence of other androgen receptor associated coregulators. This protein may act as a nucleus-localized, basic transcriptional factor and also as a bifunctional transcriptional regulator. Mutations of this gene have been associated with Sotos syndrome and Weaver syndrome. One version of childhood acute myeloid leukemia is the result of a cryptic translocation with the breakpoints occurring within nuclear receptor-binding Su-var, enhancer of zeste, and trithorax domain protein 1 on chromosome 5 and nucleoporin, 98-kd on chromosome 11. Two transcript variants encoding distinct isoforms have been identified for this gene.
Aliases: nuclear receptor binding SET domain protein 1
- UniProt
- Q96L73
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