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ARHGEF3 抗体

ARHGEF3 适用: 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6571793
发货至: 中国
  • 抗原 See all ARHGEF3 抗体
    ARHGEF3 (rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3))
    适用
    • 35
    • 5
    • 4
    • 1
    人, 小鼠
    宿主
    • 32
    • 3
    克隆类型
    • 34
    多克隆
    标记
    • 18
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ARHGEF3 antibody is un-conjugated
    应用范围
    • 26
    • 22
    • 20
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    纯化方法
    Affinity purification
    免疫原
    Recombinant fusion protein of human ARHGEF3 (NP_062455.1).
    亚型
    IgG
    Top Product
    Discover our top product ARHGEF3 Primary Antibody
  • 应用备注
    WB 1:500-1:2000 IHC 1:50-1:200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    ARHGEF3 (rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3))
    别名
    ARHGEF3 (ARHGEF3 产品)
    别名
    MGC82822 antibody, ARHGEF3 antibody, si:ch211-258l4.8 antibody, MGC108040 antibody, DKFZp459N027 antibody, GEF3 antibody, STA3 antibody, XPLN antibody, 1200004I24Rik antibody, 9830169H03Rik antibody, C76747 antibody, Xpln antibody, Rho guanine nucleotide exchange factor (GEF) 3, gene 1 S homeolog antibody, Rho guanine nucleotide exchange factor 3 antibody, Rho guanine nucleotide exchange factor (GEF) 3 antibody, Rho guanine nucleotide exchange factor (GEF) 3, gene 1 antibody, arhgef3.1.S antibody, ARHGEF3 antibody, arhgef3 antibody, arhgef3.1 antibody, Arhgef3 antibody
    背景
    Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. This gene encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: RHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    分子量

    Observed_MW: 60kDa

    Calculated_MW: 36kDa/59kDa/60kDa/63kDa

    基因ID
    50650
    UniProt
    Q9NR81
    途径
    Neurotrophin Signaling Pathway
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