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ARHGEF3 抗体 (AA 211-240)

ARHGEF3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB27451 unconjugated
产品编号 ABIN652003
发货至: 中国
  • 抗原 See all ARHGEF3 抗体
    ARHGEF3 (rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3))
    抗原表位
    • 6
    • 6
    • 6
    • 6
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 211-240
    适用
    • 34
    • 5
    • 4
    • 1
    宿主
    • 31
    • 3
    克隆类型
    • 33
    多克隆
    标记
    • 17
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ARHGEF3 antibody is un-conjugated
    应用范围
    • 25
    • 22
    • 20
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    预测反应
    M
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This ARHGEF3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 211-240 amino acids from the Central region of human ARHGEF3.
    克隆位点
    RB27451
    亚型
    Ig Fraction
    Top Product
    Discover our top product ARHGEF3 Primary Antibody
  • 应用备注
    WB: 1:1000. IHC-P: 1:50~100
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    有效期
    6 months
  • Liu, Zheng, Cai, Guo, Lin, Chen, Liao, Kung, Zeng, Xie: "The putative tumor activator ARHGEF3 promotes nasopharyngeal carcinoma cell pathogenesis by inhibiting cellular apoptosis." in: Oncotarget, Vol. 7, Issue 18, pp. 25836-48, (2017) (PubMed).

  • 抗原
    ARHGEF3 (rho Guanine Nucleotide Exchange Factor (GEF) 3 (ARHGEF3))
    别名
    ARHGEF3 (ARHGEF3 产品)
    别名
    MGC82822 antibody, ARHGEF3 antibody, si:ch211-258l4.8 antibody, MGC108040 antibody, DKFZp459N027 antibody, GEF3 antibody, STA3 antibody, XPLN antibody, 1200004I24Rik antibody, 9830169H03Rik antibody, C76747 antibody, Xpln antibody, Rho guanine nucleotide exchange factor (GEF) 3, gene 1 S homeolog antibody, Rho guanine nucleotide exchange factor 3 antibody, Rho guanine nucleotide exchange factor (GEF) 3 antibody, Rho guanine nucleotide exchange factor (GEF) 3, gene 1 antibody, arhgef3.1.S antibody, ARHGEF3 antibody, arhgef3 antibody, arhgef3.1 antibody, Arhgef3 antibody
    背景
    Rho-like GTPases are involved in a variety of cellular processes, and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity. Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP. This gene encodes a guanine nucleotide exchange factor, which specifically activates two members of the Rho GTPase family: RHOA and RHOB, both of which have a role in bone cell biology. It has been identified that genetic variation in this gene plays a role in the determination of bone mineral density (BMD), indicating the implication of this gene in postmenopausal osteoporosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    分子量
    59783
    基因ID
    50650
    NCBI登录号
    NP_001122087, NP_001122088, NP_062455
    UniProt
    Q9NR81
    途径
    Neurotrophin Signaling Pathway
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