AIRE 抗体
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- 抗原 See all AIRE 抗体
- AIRE (Autoimmune Regulator (AIRE))
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This AIRE antibody is un-conjugated
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应用范围
- Immunofluorescence (IF)
- 纯化方法
- Affinity purification
- 免疫原
- A synthetic peptide of human AIRE (NP_000374.1).
- 亚型
- IgG
- Top Product
- Discover our top product AIRE Primary Antibody
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- 应用备注
- IF 1:50-1:200
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- AIRE (Autoimmune Regulator (AIRE))
- 别名
- AIRE (AIRE 产品)
- 别名
- AIRE1 antibody, APECED antibody, APS1 antibody, APSI antibody, PGA1 antibody, autoimmune regulator antibody, autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy) antibody, AaeL_AAEL013794 antibody, CpipJ_CPIJ001208 antibody, CpipJ_CPIJ001209 antibody, AIRE antibody, Aire antibody
- 背景
- This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED).
- 分子量
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Observed_MW: 55kDa
Calculated_MW: 25kDa/35kDa/36kDa/57kDa
- 基因ID
- 326
- UniProt
- O43918
- 途径
- Chromatin Binding
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