TNFRSF1B 抗体
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- 抗原 See all TNFRSF1B 抗体
- TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TNFRSF1B antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 纯化方法
- Affinity purification
- 免疫原
- Recombinant protein of human TNFRSF1B
- 亚型
- IgG
- Top Product
- Discover our top product TNFRSF1B Primary Antibody
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- 应用备注
- WB 1:500 - 1:2000 IF 1:50 - 1:200
- 限制
- 仅限研究用
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- 浓度
- 1 mg/mL
- 缓冲液
- Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- 抗原
- TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))
- 别名
- TNFRSF1B (TNFRSF1B 产品)
- 别名
- CD120b antibody, TBPII antibody, TNF-R-II antibody, TNF-R75 antibody, TNFBR antibody, TNFR1B antibody, TNFR2 antibody, TNFR80 antibody, p75 antibody, p75TNFR antibody, TNF-RII/TNFRSF1B antibody, TNFR-II antibody, TNFRSF1B antibody, TNF-R2 antibody, TNF-alphaR2 antibody, TNFRII antibody, TNFalpha-R2 antibody, Tnfr-1 antibody, Tnfr2 antibody, rank antibody, zgc:163064 antibody, TNF receptor superfamily member 1B antibody, tumor necrosis factor receptor superfamily, member 1b antibody, tumor necrosis factor receptor superfamily, member 1B antibody, TNFRSF1B antibody, Tnfrsf1b antibody, tnfrsf1b antibody
- 背景
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Synonyms: CD120b,p75,p75 TNF receptor,p75TNFR,p80 TNF alpha receptor,p80 TNF-alpha receptor,Soluble TNFR1B variant 1,TBP-2,TBPII,TNF R II,TNF R2,TNF R75,TNF-R2,TNF-RII,TNFBR,TNFR-II,TNFR1B,TNFR2,TNFR80,TNFRII,Tnfrsf1b,TNR1B,Tumor necrosis factor beta receptor,Tumor necrosis factor receptor 2,Tumor necrosis factor receptor superfamily member 1B,Tumor necrosis factor receptor type II,Tumor necrosis factor-binding protein 2
Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways.
- 分子量
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Observed_MW: 65kDa
Calculated_MW: 28kDa/48kDa
- 基因ID
- 7133
- UniProt
- P20333
- 途径
- NF-kappaB Signaling, Apoptosis, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Ubiquitin Proteasome Pathway
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