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beta Arrestin 1 抗体

ARRB1 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN5962975
发货至: 中国
  • 抗原 See all beta Arrestin 1 (ARRB1) 抗体
    beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))
    适用
    • 73
    • 46
    • 32
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 80
    • 8
    • 1
    克隆类型
    • 73
    • 16
    多克隆
    标记
    • 52
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This beta Arrestin 1 antibody is un-conjugated
    应用范围
    • 68
    • 34
    • 32
    • 26
    • 15
    • 14
    • 13
    • 12
    • 8
    • 7
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    纯化方法
    Affinity purification
    免疫原
    Recombinant protein of human ARRB1
    亚型
    IgG
    Top Product
    Discover our top product ARRB1 Primary Antibody
  • 应用备注
    WB 1:500 - 1:2000 IHC 1:50 - 1:200
    限制
    仅限研究用
  • 浓度
    1 mg/mL
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol,  pH 7.3.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))
    别名
    ARRB1 (ARRB1 产品)
    别名
    arrb1 antibody, MGC83787 antibody, arb1 antibody, arr1 antibody, barr1 antibody, betaarr1 antibody, 1200006I17Rik antibody, AW208571 antibody, G430100A01Rik antibody, ARB1 antibody, ARR1 antibody, BARRES antibody, arrestin beta 1 antibody, arrestin, beta 1 antibody, arrestin beta 1 L homeolog antibody, beta-arrestin 1 antibody, putative beta-arrestin 1 antibody, ARRB1 antibody, arrb1 antibody, arrb1.L antibody, CpipJ_CPIJ016988 antibody, CpipJ_CPIJ017114 antibody, Smp_122900 antibody, Smp_126080 antibody, Smp_176980 antibody, Smp_152290 antibody, Arrb1 antibody
    背景

    Synonyms: ARB1,ARR1,ARRB1,ARRB1,Arrestin 2,Arrestin beta 1,Arrestin beta-1,Beta-arrestin-1

    Background: Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described.

    分子量

    Observed_MW: 43-54kDa

    Calculated_MW: 46kDa/47kDa

    基因ID
    408
    UniProt
    P49407
    途径
    Positive Regulation of Peptide Hormone Secretion, Nuclear Hormone Receptor Binding, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction
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