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beta Arrestin 1 抗体 (C-Term)

Name: beta Arrestin 1 抗体 (C-Term)
SKU: ABIN655944
Availability: OutOfStock

ARRB1 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB31615 unconjugated

All lanes : Anti-ARRB1 Antibody (C-term) at 1:1000 dilution + mouse liver lysate Lysates/proteins at 20 μg per lane. (beta Arrestin 1 抗体 (C-Term))

ARRB1 Antibody (C-term) (ABIN655944 and ABIN2845333) flow cytometric analysis of A549 cells (right histogram) compared to a negative control cell (left histogram). (beta Arrestin 1 抗体 (C-Term))

FACS

ARRB1 Antibody (C-term) (ABIN655944 and ABIN2845333) western blot analysis in A549 cell line lysates (35 μg/lane). (beta Arrestin 1 抗体 (C-Term))

Confocal immunofluorescent analysis of ARRB1 Antibody (C-term) (ABIN655944 and ABIN2845333) with A549 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). (beta Arrestin 1 抗体 (C-Term))

ARRB1 Antibody (C-term) (ABIN655944 and ABIN2845333) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. (beta Arrestin 1 抗体 (C-Term))

IHC (p)

5 images

产品编号 ABIN655944

发货至: 中国

Datasheet as PDF

抗原 See all beta Arrestin 1 (ARRB1) 抗体

beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))
抗原表位
19

12

7

7

5

4

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
AA 336-363, C-Term
适用
73

46

32

6

3

3

2

2

2

1

1

1

1
人
宿主
80

8

1
兔
Compatible Secondaries
克隆类型
72

17
多克隆
标记
52

5

4

3

3

3

3

3

3

3

1

1

1

1

1

1

1
This beta Arrestin 1 antibody is un-conjugated
应用范围
68

34

32

26

15

14

13

12

9

7

3

1

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

预测反应

B, M, Rb, Rat

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This ARRB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-363 amino acids from the C-terminal region of human ARRB1.

克隆位点

RB31615

亚型

Ig Fraction

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anti-Arrestin, beta 1 (ARRB1) (AA 169-418) antibody
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anti-Arrestin, beta 1 (ARRB1) antibody
ARRB1 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IP, FACS, ICC 宿主: 兔 Monoclonal unconjugated

anti-Arrestin, beta 1 (ARRB1) (AA 1-260) antibody
ARRB1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Arrestin, beta 1 (ARRB1) antibody
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anti-Arrestin, beta 1 (ARRB1) (AA 369-418) antibody
ARRB1 适用: 人 WB, IHC, ELISA, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Arrestin, beta 1 (ARRB1) (AA 343-371), (C-Term) antibody
ARRB1 适用: 人 WB, IF, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated

anti-Arrestin, beta 1 (ARRB1) antibody
ARRB1 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Arrestin, beta 1 (ARRB1) (Ser157) antibody
ARRB1 适用: 人, 猴 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Arrestin, beta 1 (ARRB1) (C-Term) antibody
ARRB1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
抗原

beta Arrestin 1 (ARRB1) (Arrestin, beta 1 (ARRB1))

别名

ARRB1 (ARRB1 产品)

别名

arrb1 antibody, MGC83787 antibody, arb1 antibody, arr1 antibody, barr1 antibody, betaarr1 antibody, 1200006I17Rik antibody, AW208571 antibody, G430100A01Rik antibody, ARB1 antibody, ARR1 antibody, BARRES antibody, arrestin beta 1 antibody, arrestin, beta 1 antibody, arrestin beta 1 L homeolog antibody, beta-arrestin 1 antibody, putative beta-arrestin 1 antibody, ARRB1 antibody, arrb1 antibody, arrb1.L antibody, CpipJ_CPIJ016988 antibody, CpipJ_CPIJ017114 antibody, Smp_122900 antibody, Smp_126080 antibody, Smp_176980 antibody, Smp_152290 antibody, Arrb1 antibody

背景

Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described, however, their exact functions are not known.

分子量

47066

基因ID

408

NCBI登录号

NP_004032, NP_064647

UniProt

P49407

途径

Positive Regulation of Peptide Hormone Secretion, Nuclear Hormone Receptor Binding, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction