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IL-1 beta 抗体 (AA 148-174)

Name: IL-1 beta 抗体 (AA 148-174)
SKU: ABIN652470
Availability: OutOfStock

This anti-IL-1 beta antibody is a 兔多克隆 antibody detecting IL-1 beta in WB, FACS 和 IHC (p). Suitable for 人和小鼠. This Primary Antibody has been cited in 4+ publications.

All lanes : Anti-IL1B Antibody (Center) at 1:2000 dilution Lane 1: human spleen lysate Lane 2: mouse brain lysate Lysates/proteins at 20 μg per lane. (IL-1 beta 抗体 (AA 148-174))

Formalin-fixed and paraffin-embedded human lung carcinoma with IL1B Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. (IL-1 beta 抗体 (AA 148-174))

IHC (p)

Western blot analysis of IL1B Antibody (Center) (ABIN652470 and ABIN2842321) in NCI- cell line lysates (35 μg/lane). (IL-1 beta 抗体 (AA 148-174))

Overlay histogram showing MCF-7 cells stained with (ABIN652470 and ABIN2842321) (green line). (IL-1 beta 抗体 (AA 148-174))

FACS

4 images

(4 references)

产品编号 ABIN652470

发货至: 中国

Datasheet as PDF

Quick Overview for IL-1 beta 抗体 (AA 148-174) (ABIN652470)

抗原

See all IL-1 beta (IL1B) 抗体

IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

适用

人, 小鼠

宿主

兔

克隆类型

多克隆

标记

This IL-1 beta antibody is un-conjugated

应用范围

Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB21917

Discover our top product IL1B Primary Antibody

抗原表位
26

24

15

15

15

12

11

9

7

7

6

6

6

6

5

4

4

4

3

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
AA 148-174

预测反应

Pr, Rb

纯化方法

This antibody is purified through a protein A column, followed by peptide affinity purification.

免疫原

This IL1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 148-174 amino acids of human IL1B.

亚型

IgG
anti-Interleukin 1, beta (IL1B) (AA 101-200) antibody
IL1B 适用: 人, 小鼠, 大鼠, 兔, Cow, Pig WB, ELISA, FACS, IF (p), IHC (p), IF (cc), IHC (fro), DB 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 1, beta (IL1B) antibody
IL1B 适用: 人 IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 3A6 unconjugated

anti-Interleukin 1, beta (IL1B) (AA 161-269) antibody
IL1B 适用: 人, 小鼠, 大鼠, 兔, Cow WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 1, beta (IL1B) (AA 170-269) antibody
IL1B 适用: 人 WB, ELISA, IP, IF 宿主: 小鼠 Monoclonal 2A8 unconjugated

anti-Interleukin 1, beta (IL1B) (AA 117-269) antibody
IL1B 适用: 人 IHC, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 6F12D5 unconjugated

anti-Interleukin 1, beta (IL1B) (AA 117-269) antibody
IL1B 适用: 人 ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 5C3B7 unconjugated

anti-Interleukin 1, beta (IL1B) (AA 1-266) antibody
IL1B 适用: 绵羊 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 1, beta (IL1B) (AA 1-269) antibody
IL1B 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 1, beta (IL1B) (AA 148-174) antibody
IL1B 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 1, beta (IL1B) (AA 1-269) antibody
IL1B 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:2000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:25

限制

仅限研究用
状态

Liquid

缓冲液

Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

有效期

6 months
Abdul-Muneer, Alikunju, Mishra, Schuetz, Szlachetka, Burnham, Haorah: "Activation of NLRP3 inflammasome by cholesterol crystals in alcohol consumption induces atherosclerotic lesions." in: Brain, behavior, and immunity, Vol. 62, pp. 291-305, (2018) (PubMed).

Liu, Wen, Chen, Wang, Huang, Tu: "Effects of Berberine on NLRP3 and IL-1β Expressions in Monocytic THP-1 Cells with Monosodium Urate Crystals-Induced Inflammation." in: BioMed research international, Vol. 2016, pp. 2503703, (2016) (PubMed).

Zhang, Liu, Huang, Su, Zhang, Wang, Li: "NF-?B activation and cell death after intracerebral hemorrhage in patients." in: Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, Vol. 35, Issue 7, pp. 1097-102, (2014) (PubMed).

Liu, Tu, Chen, Wang, Hu, Dong: "Effects of Modified Simiao Decoction on IL-1 β and TNF α Secretion in Monocytic THP-1 Cells with Monosodium Urate Crystals-Induced Inflammation." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2014, pp. 406816, (2014) (PubMed).
抗原

IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

别名

IL1B

背景

IL1B is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (,CNS), is found to contribute to inflammatory pain hypersensitivity.

分子量

30748

基因ID

3553

NCBI登录号

NP_000567

UniProt

P01584

途径

NF-kappaB Signaling, Interferon-gamma Pathway, TLR signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome